Medication info
Lozapa Tablets (Losartan Potassium)

Lozapa Tablets (Losartan Potassium)

Prescription medicationTablet경구
Ingredient · strength
Losartan Potassium›50mg / 1 tablet
Manufacturer / importer
(주)한국파비스제약
Appearance
White oval film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 200600489 · Notified 2006.02.10 · Insurance code 621802070

Summary

Main use
Improvement of hypertension and type 2 diabetic nephropathy
Who takes it
Adults · Children
Adult dose
This medication can be taken regardless of meals, but it is recommended to take it at the same time each day. For hypertension treatment, the initial and maintenance dose is 50 mg of Losartan Potassium orally once daily; if the therapeutic effect is insufficient, the dose may be increased to 100 mg once daily or taken in divided doses twice daily. For treating nephropathy in patients with hypertension and type 2 diabetes, the usual initial dose is 50 mg once daily.
Child dose
For children and adolescents aged 6 years and older: (1) For patients weighing 20 kg to less than 50 kg: Administer 25 mg once daily, which may be increased up to a maximum of 50 mg once daily according to blood pressure response.

Ingredients

Manufacturer
(주)한국파비스제약

Efficacy & effects

Improvement of hypertension and type 2 diabetic nephropathy

  • Hypertension
  • nephropathy in patients with type 2 diabetes
View approved original text

Hypertension is a critical condition that plays an important role in controlling blood pressure within normal ranges to reduce the burden on the heart and blood vessels. Treating hypertension not only prevents cardiovascular diseases but also has significant effects in protecting kidney function in patients with type 2 diabetes. This medication helps control blood pressure in hypertensive patients and prevent kidney complications caused by diabetes. Therefore, it is suitable for individuals with hypertension who have concerns about kidney problems due to diabetes. Overall, it aids in managing both blood pressure and kidney health, thereby improving the overall health status of patients.

How to take

Adult dose

This medication can be taken regardless of meals, but it is recommended to take it at the same time each day. For hypertension treatment, the initial and maintenance dose is 50 mg of Losartan Potassium orally once daily; if the therapeutic effect is insufficient, the dose may be increased to 100 mg once daily or taken in divided doses twice daily. For treating nephropathy in patients with hypertension and type 2 diabetes, the usual initial dose is 50 mg once daily.

Child dose

For children and adolescents aged 6 years and older: (1) For patients weighing 20 kg to less than 50 kg: Administer 25 mg once daily, which may be increased up to a maximum of 50 mg once daily according to blood pressure response.

Precautions

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters; therefore, it should not be used by pregnant women or women who may become pregnant. Patients with an allergy to this medication, severely reduced liver function, certain genetic disorders, and specific heart and kidney diseases should not use this medication. Elderly patients, patients with weakened kidney function, and patients with hyperkalemia should use this medication with caution. The risk of side effects may increase when this medication is combined with other antihypertensive agents or certain medications, so careful administration is required. This medication is generally well tolerated, but side effects such as dizziness, muscle pain, cough, and dyspepsia may occur, and rarely serious side effects like angioedema, liver dysfunction, or kidney failure can occur. Careful monitoring of blood pressure and kidney function is required during treatment as blood pressure may drop too low or kidney function may deteriorate rapidly. This medication can increase potassium levels, so it should not be taken with potassium supplements or medications containing potassium; patients at risk for hyperkalemia should frequently check serum potassium levels. It is advisable to avoid grapefruit juice while taking this medication, and it is recommended to temporarily discontinue it before surgery. Women who are pregnant or breastfeeding should always consult their physician, and if pregnancy is confirmed, this medication should be stopped immediately. Children, particularly those under 6 years of age, and adolescents with severely impaired kidney function should not use this medication. In case of overdose, symptoms of hypotension and bradycardia may occur, and immediate medical attention should be sought for appropriate treatment. This medication should be kept out of reach of children, and transferring it to another container is not advisable for maintaining quality and safety.

Side effects and when to seek care immediately

Serious side effects

Hives, angioedema (severe swelling), difficulty breathing, chest tightness, cold sweats, paleness, severe allergic reactions, severe skin adverse reactions (severe rash, blisters, skin peeling, pain in mucous membranes of mouth/eyes), shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, jaundice (yellowing of skin or eyes), generalized weakness, sudden and very severe headache, lightning headache, seizures, confusion.

Mild side effects

  • Muscle cramps
  • back pain
  • leg pain
  • dizziness
  • nasal congestion
  • upper respiratory infection
  • sinusitis
  • nausea
  • diarrhea
  • dyspepsia
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  • cough
  • sinus dysfunction
  • pharyngitis
  • muscle pain
  • insomnia
  • headache
  • weakness/fatigue
  • swelling/edema
  • abdominal pain
  • chest pain
  • swelling of the lips/eyelids
  • facial rash
  • desquamation of palms
  • hemolysis
  • facial swelling
  • fever
  • orthostatic effects
  • syncope
  • angina
  • second-degree heart block
  • cerebrovascular accident
  • hypotension
  • myocardial infarction
  • atrial fibrillation.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it should be stored in a tightly closed container. Additionally, it is important to keep it in a dry place between 15 degrees and 30 degrees to maintain its effectiveness.

Appearance and packaging

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.