Uretool SR Tablet 4mg (Tolterodine L-Tartrate)

Adult dose

Adults: Administer 4 mg orally once daily as tolterodine L-tartrate. Patients with renal impairment, hepatic impairment, or receiving ketoconazole or another potent CYP3A4 inhibitor: Administer 2 mg once daily as this drug. If adverse reactions occur, the dose may be reduced from 4 mg to 2 mg once daily. This drug may be taken with or without food. Swallow the dosage form whole; do not crush or split it.

This medicine should not be administered to patients with certain conditions. For example, it should not be used in patients with urinary retention symptoms, patients with gastric retention symptoms, patients with uncontrolled glaucoma, patients allergic to this medication or its components, patients with severe myasthenia gravis, or those with severe ulcerative colitis or toxic megacolon. Moreover, caution is advised in patients at risk of urinary retention, those with gastrointestinal obstruction, impaired kidney or liver function, and those taking certain medications such as antibiotics, antifungals, or immunosuppressants. Patients with autonomic neuropathy or at risk for decreased gastrointestinal motility should also be treated carefully. This medication may cause mild side effects such as dry mouth, dyspepsia, and reduced tear production. Other reported adverse reactions include infections, allergic reactions, dizziness, drowsiness, headaches, constipation, urination problems, chest pain, fatigue, visual disturbances, and dry skin. Particularly, this medication may prolong the QT interval, thus caution is needed for patients with heart disease, those with a prolonged QT interval, those taking certain antiarrhythmics, or patients with electrolyte imbalances. This medication may require caution when driving or operating machinery. Additionally, before starting treatment, a thorough assessment of bladder issues or causes of urgency and frequency should be conducted. Co-administration with other antimuscarinic agents may enhance effects, while in contrast, some drug combinations may reduce effects. There is also potential interaction with medications metabolized by the liver and kidneys, so it is essential to inform the healthcare provider of all medications being taken. It is advisable for pregnant or nursing women to avoid this medication, as it may affect the fetus, particularly during the first trimester. Safety and efficacy in children have not been established, so this medication is not to be used in pediatric patients. In case of overdose, serious side effects such as vision problems or urinary difficulties may occur; immediate medical attention is required, and gastric lavage or treatment for drug toxicity may be necessary. Finally, this medication should be stored out of the reach of children, and transferring it to another container should be avoided to prevent quality degradation or accident risks.

• dry mouth
• indigestion
• decreased tear production
• bronchitis
• allergic reactions
• confusion
• drowsiness
• dizziness
• headache
• irritability

This medication may be sensitive to air or moisture; therefore, it should be stored in a tightly closed container. To maintain the efficacy of the medication, it is best stored at room temperature below 25 degrees Celsius.

Appearance

White circular film-coated tablet

Package unit

30 tablets/bottle