Famvir Tablet (Famciclovir)

Adult dose

1. Treatment of herpes zoster Adults: Administer 250 mg of famciclovir orally 3 times daily for 7 days. It is preferable to start treatment as soon as symptoms appear after infection. 2. Treatment of an initial episode of genital herpes Adults: Administer 250 mg of this drug orally 3 times daily for 5 days. It is preferable to start treatment as soon as symptoms appear after infection. 3. Treatment of acute recurrent genital herpes Adults: Administer 125 mg of this drug orally 2 times daily for 5 days. It is preferable to start treatment during the prodromal period or as soon as symptoms appear after infection. 4. Suppression of recurrent genital herpes Adults: Administer 250 mg of this drug orally 2 times daily. Discontinue treatment periodically every 6～12 months to observe whether the natural course of the disease has changed. 5. Patients with renal impairment: Since the clearance of this drug is reduced in patients with renal impairment, adjust the dose with caution. The dosage and administration for these patients are as follows. 1) Treatment of herpes zoster and an initial episode of genital herpes: Creatinine clearance (mL/min/1.73㎡) Dose 30～59 250 mg per dose, 2 times daily 10～29 250 mg per dose, once daily 2) Treatment of acute recurrent genital herpes: Creatinine clearance (mL/min/1.73㎡) Dose 30～59 125 mg per dose, 2 times daily 10～29 125 mg per dose, once daily 3) Suppression of recurrent genital herpes: Creatinine clearance (mL/min/1.73㎡) Dose 30～59 250 mg per dose, 2 times daily 10～29 125 mg per dose, 2 times daily 4) If only serum creatinine is known, creatinine clearance can be calculated using the following equations. Men: {body weight (kg) × (140-age)}/ {72 × serum creatinine (mg/dL)} Women: 0.85 × the value calculated for men 5) Patients with renal impairment undergoing hemodialysis For patients undergoing hemodialysis, it is preferable to administer this drug every 48 hours, taking the dialysis interval into account. Since 4 hours of hemodialysis reduces the plasma concentration of this drug by approximately 75%, administer this drug immediately after dialysis. The recommended dose is 250mg for patients with herpes zoster and 125mg for patients with genital herpes. 6. Patients with hepatic impairment: No dose adjustment is required in patients with chronic compensated liver disease. There is insufficient treatment experience in patients with overt chronic decompensated liver disease; therefore, no clear recommended dose has been established.

This medication should not be used by patients who have had allergic reactions to this drug or its components. Additionally, this medication contains lactose, so it should not be administered to patients with genetic disorders that prevent lactose digestion. Patients with impaired kidney function should exercise caution when using this medication, and dosage adjustments may be necessary. While taking this medication, symptoms like headache, nausea, dizziness, drowsiness may occur; consult a doctor if symptoms are severe. Adverse reactions such as liver dysfunction or skin rash, itching may occur, so any abnormal symptoms should be reported immediately. This drug does not completely cure genital herpes, thus there is still a risk of transmission during sexual contact, so safe sexual practices should be maintained. It is advisable to avoid driving or operating machinery if experiencing dizziness or drowsiness. Women who are pregnant or breastfeeding should consult a doctor before using this medication to determine whether to use it. It is preferable not to use this medication in children under 18 years of age as its safety and efficacy have not been established. In case of overdose, immediate medical attention should be sought, and blood dialysis may help reduce drug concentration. This medication should be stored in a dry place at temperatures below 30 degrees Celsius and kept out of reach of children, and it is advisable not to transfer it to another container.

headache

This medication should be stored in a tightly sealed container to prevent air or moisture from entering, and it is recommended to keep it in a cool, dry place below 30 degrees Celsius. Storing it this way helps maintain the effectiveness of the drug for a longer period.

Appearance

White round film-coated tablet

Package unit

21 tablets (7 tablets/PTP x 3)