Lozatol (Losartan Potassium)

Adult dose

This medication can be taken with or without food, but it is recommended to take it at the same time each day. 1. Hypertension - The initial and maintenance dosage as losartan potassium is recommended as 50 mg orally once daily. - Maximum blood pressure lowering effect typically occurs 3 to 6 weeks after starting therapy. - If the therapeutic effect is insufficient, the same dose may be divided and taken twice daily or increased to 100 mg once daily if necessary.

Child dose

Pediatrics and adolescents aged 6 years and older (1) Weight 20 kg or more and less than 50 kg: administer 25 mg once daily, which may be increased to a maximum of 50 mg once daily based on blood pressure response. (2) Weight

This medication should be discontinued immediately if pregnancy is confirmed, particularly during the second and third trimesters, as it may impair fetal kidney function and can lead to serious injury or death. If taken during pregnancy, it may inhibit fetal lung development and cause skeletal deformities, as well as raise risks of decreased skull formation, renal failure, and hypotension in newborns. This medication should not be given to patients with hypersensitivity, severe liver impairment, hereditary angioedema, or primary hyperaldosteronism. Patients with genetic issues such as lactose intolerance should also avoid this medication. Elderly patients, those with hyperkalemia, liver impairment, heart valve abnormalities, or decreased kidney function should use this medication with caution and have their blood pressure and kidney function checked regularly. As this medication lowers blood pressure, it may cause dizziness or fainting due to sudden drops in blood pressure. If such symptoms occur while taking the medication, consult medical personnel immediately. Because there is a risk of increased serum potassium levels, it is advisable to avoid taking potassium supplements or potassium-containing medications simultaneously. During treatment, periodic tests of liver and kidney function should be conducted to check for any abnormalities. Particularly for patients with severely reduced kidney function, caution and dosage adjustments are necessary as kidney failure may worsen with use of this medication. Some patients may experience side effects such as dry cough, dizziness, muscle pain, and dyspepsia, and if symptoms persist, they should inform medical staff. Pregnant or nursing women are advised not to take this medication, and if it is absolutely necessary, breastfeeding should be discontinued. For children under 6 years of age or those with severe kidney impairment, the safety and efficacy of this medication have not been established, and it should not be administered. In case of overdose, symptoms like hypotension and bradycardia may occur, thus strict adherence to the prescribed dosage is essential, and any unusual symptoms should prompt immediate hospital visits. It is advisable to avoid consuming grapefruit juice while taking this medication, and consult with a doctor or pharmacist regarding potential interactions with other medications being taken. This medication should be kept out of reach of children and not transferred to other containers for safety.

Serious side effects

Hives, angioedema (e.g., laryngeal edema which may obstruct the airway, facial, lip, pharyngeal, or tongue swelling), facial rash, difficulty breathing, liver dysfunction, acute hepatitis, fulminant hepatitis, jaundice, ventricular extrasystole, atrial fibrillation, myocardial infarction, cerebrovascular accident, hypotension, fainting, loss of consciousness, kidney failure, anuria, edema accompanying elevated blood pressure, vasculitis (Henoch-Schönlein purpura), anaphylaxis-like syndrome (discomfort, oral symptoms felt

Mild side effects

• Muscle cramps
• back pain
• leg pain
• dizziness
• congestion
• upper respiratory infection
• sinusitis
• nausea
• diarrhea
• dyspepsia

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is best to maintain a storage temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle