Paxar Tablet 6 mg (Lacidipine)

Adult dose

1. Adults The therapeutic dose of this medicine should be adjusted appropriately according to the patient's response and severity of symptoms. The initial dose is 2 mg of lacidipine once daily. It should be taken at the same time every day, preferably in the morning, regardless of meals. If a dose increase is needed, increase to 4 mg once daily after an appropriate period has elapsed to allow adequate assessment of the pharmacological effect. Increase to 6 mg once daily only if blood pressure is not controlled with 4 mg once daily. The period before deciding on an increase should generally be at least 3 ～ 4 weeks, the time required for this medicine to achieve its full pharmacological effect, except in patients who require a more rapid increase. If an adequate response is not achieved, another antihypertensive agent may be added (a beta-blocker and/or a diuretic). 2. Patients with hepatic impairment Because this medicine is metabolized mainly in the liver, its bioavailability and blood pressure-lowering effect may be increased in patients with hepatic impairment. These patients should be monitored carefully, and a reduction in the initial dose is recommended. 3. Patients with renal impairment Since this medicine is not excreted through the kidneys, no dose adjustment is necessary in patients with renal impairment. 4. Older adults The initial dose is 2 mg once daily. If needed, the dose may be increased to 4 mg once daily after 4 weeks.

Child dose

There is no experience with the use of this medicine in children.

This medication is used to lower blood pressure. This medication should not be used in certain patients. For example, those who are allergic to this medication or similar components, women who are pregnant or lactating, patients with serious heart problems, or those with specific heart valve diseases, may have risks when taking this medication. Additionally, patients with impaired liver function, those with issues related to heart rhythm, or unstable angina should use this medication with caution. This medication has a strong effect in lowering blood pressure and may occasionally cause dizziness, headaches, or facial flushing, which are mostly temporary. The medication may worsen angina symptoms in patients with heart disease; therefore, if symptoms worsen, it is essential to consult a doctor immediately. Also, suddenly stopping this medication may worsen symptoms, so when discontinuing, it should be done gradually under the direction of a physician. There may be interactions when taken with other medications, so it is crucial to inform the doctor or pharmacist if taking other antihypertensives, antibiotics, antidepressants, etc. Particularly, care should be taken as the effect of this medication may change when taken with grapefruit juice. This medication is not recommended for use in pregnant or nursing women, and its safety in children has not been established. In case of overdose, blood pressure may drop too low, or there may be disturbances in heart rhythm, so the dosage must be strictly followed, and if abnormal symptoms occur, medical attention should be sought immediately. Lastly, it is advised to keep this medication out of reach of children and not to transfer it to other containers.

• Dizziness
• headache
• mood disturbances
• tremor
• depression
• palpitations
• tachycardia
• flushing
• exacerbation of pre-existing angina
• syncope

This medication should be stored in a container that protects it from light and air, at room temperature between 1 and 30 degrees Celsius. This ensures that the effectiveness of the medication is well maintained and it can be used safely.

Appearance

White, oval film-coated tablet with a biconvex shape

Package unit

28 tablets (7 tablets/PTP x 4)