Trison Kit 2 Gram Injection

Adult administration

For adults and children over 12 years, administer 1-2 g (potency) of ceftriaxone via intravenous injection once daily. For infections caused by severe pathogens or those showing moderate susceptibility, the dose may be increased to 4 g (potency) once daily. Elderly patients should follow the adult dosing regimen without changes. To prevent infections before and after surgery, a single dose of 1-2 g (potency) should be administered 30-90 minutes prior to surgery. For renal and...

Child administration

For newborns (within 14 days of birth), administer 20-50 mg (potency) per kg of body weight once a day, not to exceed 50 mg (potency) per kg. For infants and children (15 days to 12 years), administer based on body weight.

This drug must not be mixed or administered simultaneously with solutions or medications containing calcium. In particular, it should never be administered to newborns, as the drug can precipitate when combined with calcium, causing severe side effects. It should not be used in patients with hypersensitivity to this drug or those allergic to cephalosporins or penicillin antibiotics. Additionally, it should not be given to premature infants, newborns with jaundice or hypoalbuminemia, and newborns receiving calcium solutions. Caution is advised for patients with a history of drug allergies, allergic constitution, or severe renal impairment, and dosage adjustment and modification of administration intervals may be necessary. Regular blood tests and evaluations of liver and kidney function are important while using this drug to detect adverse reactions early. The drug may cause various side effects, such as pain at the injection site, rash, diarrhea, increased liver enzymes, and decreased blood cells, so symptoms should be reported immediately. If allergic reactions or shock symptoms occur, administration should be stopped immediately, and emergency treatment should be sought. This drug may affect the nervous system, causing dizziness or headaches; caution should be exercised when driving or operating machinery. Women who are pregnant or breastfeeding should consult a physician before using this drug, and it should not be given to newborns and premature infants due to the risk of bilirubin encephalopathy. Moreover, it is administered only by intravenous injection, employing separate injection ports for calcium-containing solutions while thoroughly cleaning the injection ports before and after use. There is no antidote for overdose, so treatment should be symptomatic, and interactions with other medications should be carefully monitored. Particularly, patients with impaired renal function or the elderly require careful dosage adjustments and monitoring.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, cough with fever and respiratory abnormalities, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headaches, seizures, consciousness disturbances, visual disturbances, paralysis, urinary issues.

Mild side effects

• Eosinophilia
• leukopenia
• thrombocytopenia
• diarrhea
• rash
• increased liver enzymes
• headache
• dizziness
• bronchospasm
• loose stools

This drug should be stored in a sealed container to avoid exposure to air, ideally at room temperature between 1 to 30 degrees Celsius. Proper storage preserves the drug's efficacy and prevents degradation.

Appearance

A kit injection consisting of a colorless transparent glass vial containing crystalline powder that is white to yellowish in color and a transparent polyethylene container with a solvent.

Package unit

1 kit (1 vial part + 1 solvent part) × 10