Pencra Duo Tablet 1000 mg (Amoxicillin Hydrate, Clavulanate Potassium)

Adult dose

For severe infections and respiratory infections in adults, take 1 tablet orally twice daily at 12-hour intervals.

This medicine should not be given to patients who have had hypersensitivity reactions to beta-lactam antibiotics such as penicillins or cephalosporins. Caution is required for patients with viral diseases such as infectious mononucleosis or lymphocytic leukemia, as the risk of rash may increase. Patients with a history of liver dysfunction or jaundice should avoid using this medication, as it may exacerbate symptoms. Patients with decreased liver function or severe kidney disease may have increased drug concentrations, necessitating adjustments to dosing intervals. Caution should be exercised when using this medication in patients with allergies or symptoms such as asthma or urticaria. Patients who have difficulty swallowing, elderly individuals with poor nutritional status, or those with gastrointestinal diseases require caution as they may experience vitamin K deficiency or problems with drug absorption. If symptoms such as diarrhea, abdominal pain, or blood in the stool occur during use of this medication, it should be discontinued immediately and a doctor consulted. If symptoms such as abnormal liver function, skin rash, respiratory distress, or hypersensitivity occur, immediate medical attention should be sought. Long-term use requires regular monitoring of kidney and liver function as well as blood status, and the medication should be discontinued if abnormalities occur. Pregnant women or those who may become pregnant should avoid use, especially during the first three months, and nursing mothers should be cautious as the drug may cause side effects in the infant. This medication is recommended only for children aged 12 years or older or weighing over 40 kg, and should be administered cautiously to the elderly. Due to potential interactions with other medications, it is essential to inform a physician or pharmacist about any medications currently being taken. In case of overdose, gastrointestinal symptoms, renal failure, and neurological abnormalities may occur, and immediate contact with medical personnel for appropriate treatment is required. This medication should be stored in a sealed container to prevent moisture absorption and kept in a cool, dry place below 25 degrees Celsius. Instructions from a physician must be followed before use.

Serious side effects

Urticaria, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, anaphylaxis, Stevens-Johnson syndrome, shock, severe allergic reactions, fever with severe rash, blisters, skin peeling, pain in mucous membranes of mouth/eyes, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, yellowing of skin or eyes (jaundice), severe malaise, liver injury

Mild side effects

Diarrhea, membranous colitis, indigestion, stomatitis, gastritis, glossitis, nausea, vomiting, loss of appetite, abdominal pain, abdominal bloating, constipation, colonic pain, hyperacidity, loose stools, dry mouth, acute pancreatitis, candidiasis, antibiotic-associated colitis, blood in the stool, itching, erythema multiforme, toxic epidermal necrolysis, vesicular dermatitis, acute generalized exanthematous pustulosis, eosinophilia, systemic symptoms, angioedema, serum sickness-like syndrome, hypersensitivity vasculitis, hematologic effects

This medication should be stored in a sealed container to prevent moisture absorption and kept in a cool, dry place below 25 degrees Celsius. By storing it this way, the drug's components will not change, and its effectiveness can be well maintained.

Appearance

White or nearly white oblong film-coated tablet

Package unit

40 tablets (4 tablets/PTP x 10)