Dimetin Tablet (Memantine Hydrochloride)

Adult dose

Treatment should always be initiated by a physician experienced in the diagnosis and treatment of Alzheimer's dementia, and only if the caregiver is able to periodically confirm the patient's medication adherence. This medication can be taken with or without food. Dose escalation: The maximum daily dose is 20 mg, and to minimize the risk of adverse reactions, the dose should be increased by 5 mg per week over the first 3 weeks. First week (days 1 to 7): Administer 5 mg once daily for 7 days. Second week (days 8 to 14): Administer 10 mg once daily (5 mg twice daily) for 7 days. Third week (days 15 to 21): Administer 15 mg once daily (10 mg in the morning, 5 mg in the evening) for 7 days. From the fourth week onward: Administer 20 mg once daily (10 mg twice daily). The recommended maintenance dose is 20 mg once daily (10 mg twice daily).

This medication should not be used by patients who are allergic to its components. Patients with severe liver or kidney damage should not take this medication, especially those with very low kidney function. This medication contains lactose and should not be used by patients with lactose intolerance or certain genetic metabolic disorders. Patients with epilepsy or a history of seizures should use this medication cautiously, and individuals at high risk for seizures should also be monitored closely. Using this medication in combination with other drugs that have similar effects may increase the risk of side effects, so it is advisable not to combine them. Patients with changes in urine acidity or certain kidney diseases should be carefully monitored while taking this medication. There is insufficient data for the use of this medication in patients with heart disease or uncontrolled hypertension, so it should be administered with caution. This medication may cause side effects such as dizziness, headache, constipation, drowsiness, and increased blood pressure; if these symptoms are severe, consult a physician. Rarely, symptoms such as mental confusion, hallucinations, or psychotic symptoms may occur, so if these symptoms appear, inform the healthcare provider immediately. This medication may interact with other drugs, so if you are taking other medications, be sure to inform your healthcare provider. Women who are pregnant or may become pregnant should use this medication only when the benefits outweigh the risks, as it may affect the fetus. Breastfeeding women should consider discontinuing breastfeeding while taking this medication, as it may be excreted in breast milk. The safety and effectiveness of this medication in children and adolescents under 18 years of age have not been established, so it is advisable not to use it. In case of overdose, symptoms such as confusion, drowsiness, dizziness, and vomiting may occur, and immediate emergency treatment should be sought. This medication may affect the patient's reaction time, increasing the risk of accidents while driving or operating machinery, so caution is required. Store out of reach of children, and avoid transferring the medication to other containers, as this may cause accidents or degrade the quality.

Serious side effects

• Seizure
• psychotic reactions
• hallucinations
• heart failure
• venous thrombosis/thromboembolism
• respiratory distress
• pancreatitis
• hepatitis

Mild side effects

• Dizziness
• headache
• constipation
• drowsiness
• hypertension
• fungal infection
• drug hypersensitivity
• confusion
• hallucinations
• psychotic reactions

This medication may be sensitive to air and moisture, so it should be stored in a tightly closed container. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

White oval film-coated tablets

Package unit

30 tablets (10 tablets/PTP×3) - 30 tablets/PTP[(10 tablets/PTP×3)], 30 tablets/bottle - 30 tablets/PTP, 100 tablets/bottle - 100 tablets/bottle, 500 tablets/bottle - 500 tablets/bottle