Clarithromycin 250mg Tablet

Adult dose

○ Adults : The usual dose is 250mg (potency) of clarithromycin twice daily. For severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7∼14 days. In patients with renal impairment and creatinine clearance of 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer to these patients for more than 14 days. ○ Mycobacterial infections : Administer 500mg (potency) of this medicine twice daily. In this case, it must be used in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcer : Administer 500mg (potency) of this medicine 3 times daily for 14 days in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) 3 times daily for 14 days (Days 1–14) and omeprazole 40mg once daily for 28 days (Days 1–28).

Child dose

Children aged 12 years or older: Same as adults. For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be administered to certain patients. For example, patients who have an allergy to any ingredients contained in this medication or have had hypersensitivity reactions to specific antibiotics should not use this medication. Special caution should be taken when taken with drugs that may affect cardiac rhythm, as it may pose risks. Additionally, patients with severe impairment of liver or kidney function should avoid this medication. It is advisable for pregnant or breastfeeding women not to use this medicine. Children or patients with central nervous system infections should also use this medication cautiously. This medicine may cause various side effects; therefore, if symptoms such as shortness of breath, severe allergic reactions, skin rashes, dyspepsia, or signs of liver or kidney function impairment occur, you should consult a doctor immediately. Furthermore, this medication has a high potential for drug interactions, so if you are taking any other medications, it is essential to inform your healthcare provider. Long-term or high-dose use of this medication may result in hearing problems or tinnitus, so caution is required. Elderly patients or those with compromised liver or kidney function may require dose adjustments and should follow medical advice. Finally, during the use of this medication, there may be dizziness or confusion when driving or operating machinery, so caution is necessary.

Shock, anaphylactic symptoms, shortness of breath, convulsions, flushing, rash, itching, hives, skin redness, angioedema, joint swelling, drug eruption, abdominal bloating, nausea, vomiting, dyspepsia, abdominal pain, discomfort, flatulence, diarrhea, oral mucosal erosion, upper abdominal pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, dysgeusia, appetite loss, constipation, stool discoloration, pseudomembranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltrates, interstitial pneumonia, chronic bronchitis, exacerbation of acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug eruption accompanied by eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, increased γ-GTP, elevated LDH, increased ALP, elevated total bilirubin, appetite loss, jaundice, dark urine, pruritus, abdominal tenderness, elevated serum creatinine, increased BUN, interstitial nephritis, renal failure, rhabdomyolysis, myalgia, weakness, elevated CPK, elevated myoglobin in blood and urine, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, fatigue, headache, taste distortion, hearing loss, paresthesia, arthralgia, myalgia, olfactory impairment, tinnitus, hearing impairment, hypoglycemia, tinnitus, hearing loss, vomiting, nausea, abdominal pain, petechial rash, acute generalized pustular eruption, leukopenia, neutropenia, thrombocytosis, agranulocytosis, thrombocytopenia, anaphylactic reaction, angioedema, decreased appetite, insomnia, neuroexcitability, noise diameter, psychotic disorder, confusional state, non-vestibular dizziness, drowsiness, tremor, movement disorders, loss of consciousness, vestibular dizziness, hearing impairment, hearing loss, cardiac arrest, atrial fibrillation, premature contractions, palpitations, vasodilation, asthma, nosebleeds, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, abnormal liver function tests, cholestasis, hepatitis, elevated alanine aminotransferase, elevated aspartate aminotransferase, elevated gamma-glutamyltransferase, liver failure, bullous dermatitis, hyperhidrosis, papular rash, acne, Henoch-Schonlein purpura, muscle spasms, musculoskeletal stiffness, myopathy, elevated blood urea, injection site phlebitis, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated alkaline phosphatase, elevated lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, abnormal urine color

This medication is sensitive to light and should be stored in a tightly sealed container that blocks light. It is also best to store the medication at room temperature between 15 degrees and 30 degrees.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle