Fexofenadine 180 mg Tablet (Fexofenadine Hydrochloride)

Adult dose

Adults and adolescents 12 years and older take fexofenadine hydrochloride 180 mg once daily by mouth with water before meals. Patients with renal impairment take 60 mg once daily by mouth with water before meals as a starting dose.

Child dose

Safety and efficacy in pediatric patients under 12 years old have not been established.

This medicine should not be used in patients with an allergic reaction to this drug or its components. It is also unsafe to administer to patients with severely impaired renal function. Caution should be exercised when using in elderly patients or those with heart disease or a history of heart disease. Side effects may occur such as headache, drowsiness, dizziness, nausea, upper respiratory infections, and lower back pain; rarely, fatigue, insomnia, nervousness, sleep disorders, nightmares, and dry mouth have been reported. Severe allergic reactions or shock may occur, so if symptoms such as difficulty breathing, low blood pressure, chest pain, or skin rash develop, administration should be stopped immediately and medical personnel informed. Liver function may be affected, so careful monitoring is needed if liver enzyme levels rise or jaundice symptoms appear, and discontinuation of the medication should be considered if necessary. This drug can affect the nervous system and digestive system, leading to headaches, dizziness, nausea, and fatigue. No reports indicate interference with driving or operating machinery, but individuals sensitive to medications should check their condition before engaging in such activities after taking the drug. This drug is not metabolized in the liver, posing a low risk for drug interactions due to liver metabolism; however, caution is required when taken alongside specific antifungals or antibiotics as blood concentration may increase. Taking this medication with antacids containing aluminum or magnesium hydroxide may reduce its absorption, so it is advisable to space these medications by 2 hours. Taking this drug with fruit juices such as grapefruit juice, orange juice, or apple juice may reduce its effectiveness, so it is recommended to take it with water. Women who are pregnant or may become pregnant should carefully consider the risks to the fetus and the benefits of treatment when taking this drug, and nursing mothers should refrain from breastfeeding while taking this medication. Safety and efficacy in children under 12 years old, newborns, and low birth weight infants have not been fully established. Elderly patients over 65 years may have a decreased renal function, so dosage adjustment and monitoring of kidney function are necessary. For skin reaction tests, including allergy tests, this medication should be stopped 3-5 days prior to testing for accurate results. In case of overdose, no specific toxic reactions have been reported; however, symptoms such as dizziness, drowsiness, and dry mouth may occur, and appropriate treatment should be provided based on the symptoms. Store out of reach of children, and do not transfer to another container to maintain quality.

Serious side effects

• Urticaria
• angioedema
• chest tightness
• difficulty breathing
• systemic hypersensitivity
• shock
• low blood pressure
• liver dysfunction
• jaundice
• systemic anaphylaxis

Mild side effects

• Headache
• drowsiness
• dizziness
• nausea
• upper respiratory infections
• lower back pain
• fatigue
• insomnia
• nervousness
• sleep disorders

This medicine should be stored in a tightly sealed container to prevent exposure to air or moisture. It is advisable to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

Pinkish rectangular film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle