Aricept 10 mg Tablets (Donepezil Hydrochloride Monohydrate)

Adult dose

As donepezil hydrochloride, administer 5 mg once daily before bedtime. If unusual dreams, nightmares, or sleep disturbances occur, consideration may be given to morning dosing. Donepezil concentration reaches a normal state 15 days after administration, so maintain the dosage at 5 mg for 4 to 6 weeks. After evaluating the clinical response, you may increase the dosage up to 10 mg, and if the dosage is increased to 10 mg per day, be cautious of gastrointestinal adverse reactions.

Child dose

No experience of use in pediatric patients.

This medication contains donepezil hydrochloride as its main ingredient and is primarily used for the treatment of Alzheimer-type dementia symptoms. First, this medication should not be used in certain patients. Individuals allergic to donepezil hydrochloride or any other components of this medication, pregnant women or women who may become pregnant, and breastfeeding women should not take this medication. It also contains lactose and should not be administered to patients with a genetic lactose intolerance. This medication should be used cautiously in patients with heart disease, history of peptic ulcer, asthma or chronic obstructive pulmonary disease, and extrapyramidal disorders such as Parkinson's disease. Particularly, in cases of heart-related issues, bradycardia or arrhythmias may occur, so caution is necessary. Various side effects may occur while taking this medication. Commonly, nausea, vomiting, diarrhea, dizziness, and insomnia may occur, while serious side effects such as severe heart problems, liver dysfunction, cerebrovascular disorders, and muscle abnormalities may occur, and if symptoms are severe, immediate consultation with a doctor is necessary. Additionally, this medication may cause cardiac conduction abnormalities, so patients with heart disease or prolonged QT intervals should regularly check their heart condition through ECG. This medication may interact with other medications, so if you are taking drugs that affect CYP3A4 or CYP2D6 enzymes, neuromuscular blocking agents, cholinergic drugs, or anticholinergic drugs, you should inform your doctor. Women who are pregnant or breastfeeding should avoid this medication, and if it is absolutely necessary to take, they should consult a specialist and consider stopping breastfeeding. Safety in children has not been established, so this medication should not be used in pediatric patients. This medication may affect driving or machine operation ability, so care should be taken at the beginning of treatment or when increasing the dose. In case of overdose, serious symptoms such as nausea, vomiting, bradycardia, and respiratory depression may occur, so you must visit a medical institution immediately for appropriate treatment. Finally, this medication should be kept out of reach of children, and transferring it to another container is not recommended as it may compromise quality.

Serious side effects

Syncope, bradycardia, heart block, QT interval prolongation, myocardial infarction, heart failure, peptic ulcer, duodenal perforation, gastrointestinal bleeding, hepatitis, liver dysfunction, jaundice, seizure, intracerebral hemorrhage, cerebrovascular disorders, severe extrapyramidal disorders, neuroleptic malignant syndrome, rhabdomyolysis, respiratory distress, acute pancreatitis, acute renal failure, sudden death, severe allergic reactions (hives, severe swelling, chest tightness, difficulty breathing, cold sweat)

Mild side effects

• Nausea
• vomiting
• diarrhea
• loss of appetite
• headache
• dizziness
• insomnia
• drowsiness
• tremors
• muscle pain

This medication should be stored in a tightly closed container to prevent air exposure and maintained at room temperature between 1°C and 30°C. Storing it this way will help maintain its effectiveness and prevent degradation.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle