Famnova Tablets 250 mg (Famciclovir)

Adult dose

1. Treatment of herpes zoster Adults: Famciclovir is administered orally at 250 mg per dose 3 times daily for 7 days. It is preferable to start treatment as soon as symptoms appear after infection. 2. Treatment of initial genital herpes infection Adults: This drug is administered orally at 250 mg per dose 3 times daily for 5 days. It is preferable to start treatment as soon as symptoms appear after infection. 3. Treatment of acute recurrent genital herpes infection Adults: This drug is administered orally at 125 mg per dose twice daily for 5 days. It is preferable to start treatment during the prodromal phase or as soon as symptoms appear after infection. 4. Suppression of recurrent genital herpes Adults: This drug is administered orally at 250 mg per dose twice daily. Treatment should be interrupted periodically every 6～12 months to assess whether the natural course of the disease has changed. 5. Patients with renal impairment: Because the clearance of this drug is reduced in patients with renal impairment, dose adjustment should be undertaken with caution. The dosage and administration for these patients are as follows. 1) Treatment of herpes zoster and initial genital herpes infection: Creatinine clearance (mL/min/1.73㎡) 30～59 250 mg per dose twice daily 10～29 250 mg per dose once daily 2) Treatment of acute recurrent genital herpes infection: Creatinine clearance (mL/min/1.73㎡) 30～59 125 mg per dose twice daily 10～29 125 mg per dose once daily 3) Suppression of recurrent genital herpes infection: Creatinine clearance (mL/min/1.73㎡) 30～59 250 mg per dose twice daily 10～29 125 mg per dose twice daily 4) If only serum creatinine is known, creatinine clearance can be calculated using the following formula. Men: {body weight (kg) × (140-age)}/ {72 × serum creatinine (mg/dL)} Women: 0.85 × the value calculated for men 5) Patients with renal impairment undergoing hemodialysis For patients undergoing hemodialysis, administration every 48 hours is preferable, taking the interval between dialysis sessions into account. Four hours of hemodialysis reduces the plasma concentration of this drug by approximately 75%; therefore, administer this drug immediately after dialysis. The recommended dose is 250mg for patients with herpes zoster and 125mg for patients with genital herpes. 6. Patients with hepatic impairment: No dose adjustment is necessary for patients with chronic compensated liver disease. There is insufficient treatment experience in patients with overt chronic decompensated liver disease; therefore, a clear recommended dose has not been established.

This medication should not be used in patients who have had allergic reactions to this drug or its ingredients. This medication contains lactose, so patients with a genetic disorder that prevents lactose digestion should also avoid taking it. Patients with allergies to soy oil, soybeans, peanuts, etc., should not use this drug. Patients with impaired kidney function or problems with fat metabolism should use this drug with caution. Headaches, nausea, dizziness, and drowsiness may occur during treatment, so it is necessary to be vigilant. This drug does not cure genital herpes; when symptoms are present, it is essential to avoid sexual contact and maintain safe sexual practices. If central nervous system symptoms such as dizziness or drowsiness occur, one should refrain from driving or operating machinery. In patients with severely impaired liver function, efficacy may be reduced, so caution is necessary. There may be potential interactions with other drugs, so special caution is needed when taken with probenecid or lamotrigine. The use of this drug in pregnant or breastfeeding women should be cautious, and it should only be used when the benefits of treatment outweigh the risks. Safety and efficacy have not been confirmed for children under 18 years, so its use is not recommended. In elderly patients, dosage adjustment is generally not necessary; however, dosage should be adjusted in the case of impaired kidney function. In the case of overdose, consult a healthcare professional immediately and receive treatment such as blood dialysis if necessary. This medication should be stored in a dry place below 30 degrees Celsius, and kept out of the reach of children. Transferring to another container is not good for maintaining quality, so caution is necessary.

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This medication should be stored in a tightly closed container to prevent air and moisture from entering. Additionally, it is advisable to store it in a cool and dry place below 30 degrees Celsius.

Appearance

White round film-coated tablet

Package unit

21 tablets / PTP packaging