Roxemisin 150 mg (Roxithromycin)

Adult dose

Adults: Administer 150㎎ (potency) of roxithromycin orally per dose, twice daily before breakfast and dinner. For pneumonia, administer 300mg (potency) once daily before breakfast. Adjust the dose appropriately according to age and symptoms.

Child dose

Children: The average dose used in clinical trials was 6mg (potency) per Kg of body weight per day. Administer 5～8mg (potency) per Kg of body weight per day orally in 2 divided doses. The doses according to body weight are as follows. Children weighing 6～11Kg: Take 25mg (potency) per dose twice daily before meals (for pediatric tablets and granules only); take 2.5mL per dose twice daily before meals (for suspension only). Children weighing 12～23Kg: Take 50mg (potency) per dose twice daily before meals (for pediatric tablets and granules only); take 5mL per dose twice daily before meals (for suspension only). Children weighing 24～40Kg: Take 100mg (potency) per dose twice daily before meals (for pediatric tablets and granules only); take 10mL per dose twice daily before meals (for suspension only).

This medication may cause severe skin reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and acute generalized exanthematous pustulosis. If progressive skin rash symptoms such as blistering or mucosal damage occur, discontinue use immediately. This medication should not be used by patients who are allergic to this drug or macrolide antibiotics, those taking specific drugs (terfenadine, astemizole, cisapride, pimobendan), or those taking ergots or mizolastine. Caution is required for patients with poor liver function, the elderly, and those taking other specific antibiotics. In particular, caution should be used in patients with arrhythmias or taking related medications due to the risk of prolonged QT interval. This medication may worsen myasthenia gravis, so patients with this condition should be careful. During use, there may be occurrences of anaphylactic shock or hypersensitivity reactions, blood abnormalities, liver dysfunction, gastrointestinal issues, severe colitis, pneumonia, neurological symptoms, sensory disorders, skin rashes, and otological or ophthalmological abnormalities, and if any abnormal symptoms arise, consult medical personnel immediately. Moreover, prolonged use of this medication may lead to resistant bacteria, so it is essential to take it for the minimum period necessary after susceptibility testing. Patients with impaired liver function should adjust their dosage while regularly monitoring liver function, while those with poor kidney function do not need dosage adjustment. This medication may interact with other drugs, so it is important to inform medical personnel when taking it with specific heart-related medications, antihistamines, anticoagulants, immunosuppressants, sedatives, or digoxin. Pregnant women or those who may become pregnant should carefully consider the benefits and risks of using this medication, and nursing mothers should avoid administration or cease breastfeeding. No dosage adjustment is required for the elderly, but they should be cautious due to the potential for dizziness or visual disturbances while operating machinery or driving. Finally, this medication should be stored out of reach of children and should not be transferred to other containers.

Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, shock, anaphylactic shock, fever, rash, allergic skin reactions, angioedema, eosinophilia, agranulocytosis, leukopenia, thrombocytopenia, cholestatic acute hepatitis, hepatocellular acute hepatitis, jaundice, elevated AST, elevated ALT, elevated ALP, increased serum bilirubin, loss of appetite, nausea, vomiting, gastric discomfort, dyspepsia, stomach pain, abdominal pain, abdominal distension, diarrhea, membranous colitis, loose stools, hemorrhagic colitis, blood in stool, pancreatitis, symptoms of membranous colitis, bronchospasm, cough, dyspnea, chest X-ray abnormalities, interstitial pneumonia, drowsiness, headache, dizziness, tongue numbness, paralysis, taste distortion, ageusia, olfactory abnormalities, anosmia, erythema multiforme, purpura, superinfection due to excessive growth of non-susceptible pathogens, transient hearing loss, auditory impairment, visual impairment, blurred vision, conjunctival injection, systemic malaise, weakness, palpitations, QT prolongation, ventricular tachycardia, arthralgia, epistaxis, menstrual irregularities, inflammation of oral and vaginal mucous membranes, hallucinations, confusion

This medication should be stored in an airtight container to protect it from air and moisture. It is crucial to maintain a storage temperature between 1 and 30 degrees Celsius to safely preserve its effectiveness.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle