Medication info
Provera Tablets 5mg (Medroxyprogesterone Acetate)

Provera Tablets 5mg (Medroxyprogesterone Acetate)

Prescription medicationTablet경구
Ingredient · strength
Medroxyprogesterone Acetate›5mg / 1 tablet
Manufacturer / importer
한국화이자제약(주)
Appearance
Blue tablet
Packaging
100 tablets (10 tablets/blister x 10)
Approval status
Active

MFDS item code 200409933 · Notified 2006.09.01 · Insurance code 648901220

Summary

Main use
Improvement of gynecological diseases such as secondary amenorrhea and functional uterine bleeding
Who takes it
Adults
Adult dose
1. Secondary amenorrhea: Administer 5 to 10 mg per day of Medroxyprogesterone Acetate orally for 5 to 10 days. For endometrial transition stimulated by endogenous or exogenous estrogen, administer 10 mg per day for 10 days. 2. Functional uterine bleeding: Administer 5 to 10 mg per day starting from the 16th or 21st day of the menstrual cycle for 5 to 10 days. For endometrial transition during the menstrual cycle

Ingredients

Importer
한국화이자제약(주)

Efficacy & effects

Improvement of gynecological diseases such as secondary amenorrhea and functional uterine bleeding

  • Secondary amenorrhea
  • functional uterine bleeding
  • mild endometriosis
  • moderate endometriosis
View approved original text

This medication is used for treating secondary amenorrhea and functional uterine bleeding caused by hormonal imbalance in the absence of pathologies such as uterine fibroids or cancer. It is also used as a combination therapy with estrogen in postmenopausal women who have not undergone hysterectomy. This efficacy effectively improves women's health issues.

How to take

Adult dose

1. Secondary amenorrhea: Administer 5 to 10 mg per day of Medroxyprogesterone Acetate orally for 5 to 10 days. For endometrial transition stimulated by endogenous or exogenous estrogen, administer 10 mg per day for 10 days. 2. Functional uterine bleeding: Administer 5 to 10 mg per day starting from the 16th or 21st day of the menstrual cycle for 5 to 10 days. For endometrial transition during the menstrual cycle

Precautions

This medication should not be used within the first 4 months of pregnancy, as using it during early pregnancy may risk fetal genital abnormalities or delay miscarriage. Exposure to this medication during pregnancy may pose potential risks to the fetus, so women who are pregnant or may become pregnant should not take this medication. This medication may cause a decrease in bone density, so it is recommended to intake sufficient calcium and vitamin D and get bone density checks, especially in long-term use cases. Use of this medication, including hormone therapy, in postmenopausal women aged 65 years and older may increase the risk of dementia. Long-term use of this medication, including hormone therapy, in postmenopausal women may increase the risk of ovarian cancer. Patients who have undergone surgery within the past week, or those with a history of cardiovascular diseases, thromboembolic disorders, liver diseases, breast cancer, etc., should not be administered this medication. Patients with risk factors for thrombosis or histories of hypertension, diabetes, liver disease, depression, etc., should be carefully monitored while using this medication. This medication can cause various side effects, such as breast pain, skin rash, thrombosis, depression, headaches, and gastrointestinal symptoms, so if any abnormal symptoms occur, consult a doctor immediately. A thorough investigation of individual and family medical history is needed before using this medication, and regular health check-ups and breast exams, as well as pelvic examinations, are recommended during treatment. After confirming pregnancy, discontinue this medication, and avoid pregnancy while taking it; if necessary, appropriate contraceptive methods should be used concurrently. This medication may interact with other drugs, so if you are taking other medications, be sure to inform your doctor or pharmacist. If breastfeeding, it is safe to discontinue breastfeeding as this medication can be transmitted through breast milk. The safety and efficacy of this medication have not been established in children under the age of 12, so it should not be used in that age group. Overdosing on this medication can lead to side effects similar to corticosteroids, so it is essential to adhere to prescribed dosages.

Side effects and when to seek care immediately

Serious side effects

Hives, angioedema, anaphylaxis, anaphylaxis-like reactions, embolism and thrombosis (deep vein thrombosis, myocardial infarction, cerebral thrombosis, cerebral embolism, thrombophlebitis, pulmonary embolism, retinal venous thrombosis, mesenteric embolism), intracranial hemorrhage, congestive heart failure, jaundice, cholestatic jaundice, dyspnea, optic neuritis, serious allergic reactions, serious skin adverse reactions, respiratory issues, liver abnormalities (jaundice), serious neurological symptoms, severe

Mild side effects

  • Breast pain
  • breast tenderness
  • lactation
  • itching
  • generalized rash
  • acne
  • erythema multiforme
  • hyperpigmentation
  • liver spots
  • hirsutism
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  • alopecia
  • palpitations
  • tachycardia
  • increased blood pressure
  • cervical erosion
  • cervical discharge
  • premenstrual syndrome
  • changes in libido
  • symptoms similar to cystitis
  • dysfunction
  • irregularities in menstrual bleeding
  • increased or decreased spotting
  • depression
  • insomnia
  • nervousness
  • feelings of unease
  • concentration difficulties
  • apathy
  • irritability
  • drowsiness

Not everyone experiences these, and they can vary from person to person.

Storage

This medication can be sensitive to air and humidity, so it should be stored in a tightly sealed container. It is also recommended to keep it at room temperature, avoiding extreme heat or cold.

Appearance and packaging

Appearance

Blue tablet

Package unit

100 tablets (10 tablets/blister x 10)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.