Provera tablets 10mg (medroxyprogesterone acetate)

Key information summary

Efficacy & effects

This medication is used to treat secondary amenorrhea and to control functional uterine bleeding due to hormonal imbalance. It also alleviates symptoms of mild to moderate endometriosis and enhances safety when used in combination with estrogen therapy in menopausal women who have not undergone hysterectomy. It is effective in improving symptoms of hormone-related disorders.

Dosage

1. Secondary amenorrhea Administer 5 to 10 mg of medroxyprogesterone acetate orally for 5 to 10 days. The optimal dose is 10 mg daily for 10 days. 2. Functional uterine bleeding Start administration of 5 to 10 mg daily for 5 to 10 days from day 16 or day 21 of the menstrual cycle. The optimal dose is 10 mg daily for 10 days starting from day 16. 3. Mild or moderate endometriosis

Precautions

This medication should not be used during the first 4 months of pregnancy. Using this medication during early pregnancy may pose risks of fetal genital abnormalities or miscarriage. Exposure to this medication during pregnancy may pose potential risks to the fetus, so pregnant women or those who may become pregnant should not take this medication. This medication may reduce bone density with long-term use, so it is advisable to intake adequate calcium and vitamin D and consider bone density tests if necessary. Postmenopausal women aged 65 and older should be careful as the use of this medication may increase the risk of dementia. Patients with a history of certain cardiovascular diseases or thrombosis, severely impaired liver function, breast cancer, or estrogen-dependent tumors should not use this medication. Patients with risk factors for thrombosis or conditions such as hypertension, diabetes, liver disease, or depression require careful monitoring by a physician when using this medication. This medication can cause various side effects, so if symptoms like skin rash, breast pain, increased blood pressure, depression, vision changes, or abnormal bleeding occur during use, it is essential to consult a doctor immediately. As this medication may interact with other drugs, it is crucial to inform the healthcare provider of any currently taken medications. Pregnant or breastfeeding women should not take this medication and should discontinue breastfeeding if they are breastfeeding. The safety and effectiveness in children under the age of 12 have not been established, so it should not be used in this age group. It is important to undergo regular health checks before and during treatment to confirm health status and consult a doctor immediately if any unusual signs appear.

Side effects

Hives, angioedema, embolism, thrombosis, cerebral thrombosis, cerebral embolism, venous thrombophlebitis, pulmonary embolism, retinal vascular thrombosis, mesenteric embolism, cerebral hemorrhage, jaundice, cholestatic jaundice, dyspnea, optic neuritis

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