Celebrex Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient. It may be taken with or without food. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily, or 100 mg twice daily. 2. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, a dose of up to 400 mg per day may be administered. If no effect is observed after 6 weeks at 400 mg per day, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea: The initial recommended dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment : For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be discussed with a doctor or pharmacist before use for those who regularly consume more than 3 alcoholic drinks a day. This medication may cause gastrointestinal bleeding, so caution is needed. Individuals with cardiovascular issues or risk factors may have an increased risk of serious thrombotic events such as myocardial infarction or stroke while taking this medication, thus it should be used at the minimum effective dose and for the shortest duration necessary. Patients should be monitored closely for cardiovascular symptoms during treatment. It may affect the gastrointestinal tract, potentially causing gastric ulcers, bleeding, or perforation, and special care should be taken for elderly patients or those with a history of gastrointestinal disease. If symptoms such as epigastric pain, indigestion, black stools, or hematemesis appear during treatment, immediate medical attention is required. This medication should not be used in patients with a history of specific allergies, severely impaired liver or kidney function, active gastrointestinal disease, heart disease, pregnant women, or nursing mothers. Patients with weakened liver or kidney function, asthma, hypertension, heart failure, or diabetes should use this medication cautiously and require regular monitoring. Dizziness and drowsiness may occur, so it is advisable to avoid driving or operating machinery during treatment. As this medication is metabolized in the liver, there may be interactions with certain drugs, and consultation with a doctor is necessary if co-administering other medications. Women who are pregnant or may become pregnant should avoid this medication, and breastfeeding women should consult with a physician before making a decision. Use in children and adolescents is not recommended due to the lack of established safety and efficacy. Elderly patients may have an increased risk of kidney, liver, or heart function decline, necessitating more caution during treatment. Regular blood tests and liver and kidney function assessments should be done for those on long-term treatment, and any abnormal signs should be reported to a doctor immediately.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle hypertonia, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, distension, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disturbances, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infection, visual confusion, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, headache, leg cramps, hypertonia, sensory decrease, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, worsening allergies, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, septicemia, sudden death, anaphylactic-like reactions, angioedema, anorexia, increased appetite, depression, neurological irritability, drowsiness, fatal intracranial hemorrhage, hallucinations, worsening epilepsy, upper respiratory infection, shingles, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, candidiasis, genital candidiasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, abnormal liver function, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased serum sodium, increased serum potassium, increased BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, increased LDH, hypoglycemia, hyponatremia, synovial bursitis, arthralgia, arthrosis, skeletal abnormalities, myalgia, cervical tension syndrome, synovitis, tendinitis, myositis, fracture, tendon rupture, pain in the back, muscle rigidity, decreased hematocrit, increased hemoglobin, petechial hemorrhages, epistaxis, thrombocytopathy, anemia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eczematous dermatitis, contact dermatitis, injection site reactions, skin nodules, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, minimal change disease, anaphylactic reactions, hallucinations, cerebral hemorrhage, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, menstrual disorders, chest pain, lethargy, drowsiness, nausea, epigastric pain, hypertension, acute renal failure, respiratory depression, coma

This medication should be stored in a sealed container that is air-tight, preferably at room temperature between 15 to 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness and prevents degradation.

Appearance

A white capsule with yellow stripes, filled with white to pale yellow powder.

Package unit

30 capsules (10 capsules/blister x 3), 100 capsules/bottle