Paromajung (Procyclidine Hydrochloride)

Adult dose

1. Parkinson's disease The optimal dose varies by patient; determine the dosage and administration accordingly. Young adult patients and patients with postencephalitic Parkinson's disease may require higher doses than elderly patients and patients with arteriosclerotic Parkinson's disease. 1) Patients not receiving other drug therapy: Initially, administer procyclidine hydrochloride 2.5 mg orally 3 times daily after meals. If the patient tolerates it well, gradually increase the dose to 5 mg per dose 3 times daily, or administer 5 mg only with the last dose. In some cases, a lower dose may provide better therapeutic effects. For patients who sometimes have difficulty adhering to bedtime dosing, it is preferable to omit the bedtime dose and divide the daily dose evenly among daytime doses. To minimize adverse reactions, take this drug during or after meals. 2) Switching from another drug therapy to procyclidine hydrochloride therapy For patients who have been continuously receiving another drug, gradually switch all or part of the other medication to this drug at 2.5 mg per dose 3 times daily. Gradually increase the dose of this drug to the required amount while correspondingly reducing the dose of the other drug or discontinuing it, until the switch is complete. 2. Extrapyramidal symptoms caused by antipsychotics (phenothiazines, reserpine, etc.) When treating extrapyramidal symptoms caused by antipsychotics during treatment of patients with psychiatric disorders, adjust the dose according to the severity of adverse reactions associated with the antipsychotic. In general, the higher the antipsychotic dose, the more severe symptoms such as rigidity and tremor become. Therefore, adjust the dose to meet each patient's needs and minimize symptoms as much as possible. To establish the daily dose of this drug, start with 2.5 mg per dose 3 times daily and increase by up to an additional 2.5 mg daily until symptoms are relieved. In most cases, a daily dose of 10～20 mg of this drug produces an excellent effect.

This medication should not be used in individuals who are allergic to this drug or its components. Additionally, it should not be administered to patients with closed-angle glaucoma with high intraocular pressure, untreated urinary retention, gastrointestinal obstruction, or severe myasthenia gravis. It should not be used in patients with severe ulcerative colitis, toxic megacolon, delayed-type dyskinesia, early dementia symptoms, dementia patients, or those with intestinal atony. Patients who are intoxicated with alcohol or certain medications (sleeping pills, antidepressants, anticonvulsants, antihistamines, sedatives) should not receive this medication. This medication contains lactose, and patients with lactose intolerance or related genetic disorders should not take it. Patients with heart disease or impaired liver or kidney function should use this medication with caution, as side effects such as tachycardia or urinary retention may occur. Elderly patients may experience psychiatric symptoms such as confusion and hallucinations, so careful monitoring is necessary. This medication may cause side effects such as dry mouth, blurred vision, dizziness, constipation, and may lead to psychological anxiety or confusion. Patients who drive or operate machinery should be cautious, as these symptoms may occur after taking this medication. Abruptly stopping this medication can worsen symptoms, so it should be discontinued gradually under the guidance of a healthcare professional. Also, taking it with other anticholinergics, central nervous system depressants, or alcohol may increase side effects, so caution is advised. Women who are pregnant or nursing should consult a physician before taking this medication, as well as children and the elderly, who may be more sensitive to it, requiring careful monitoring of dosage and condition during administration. In cases of overdose, severe neurological abnormalities, cardiac issues, and high fever may occur, requiring immediate medical treatment. This medication should be stored out of the reach of children, and transferring it to another container may affect its quality.

• Dryness of the lips
• pupillary dilatation
• blurred vision
• dizziness
• drowsiness
• nausea
• vomiting
• abdominal pain
• constipation
• agitation

This medication should be stored in a tightly closed container to protect it from air and moisture. It is important to maintain storage temperatures between 1 and 30 degrees Celsius. This will help preserve the effectiveness of the medication over time.

Appearance

Pale blue oblong tablets

Package unit

30 tablets/bottle, 500 tablets/bottle