Zocona Tablet 40 mg (Simvastatin)

Adult dose

For adult patients, the initial starting dose for the treatment of coronary artery disease and hyperlipidemia is 40 mg of simvastatin once daily. The general recommended initial starting dose for hyperlipidemia treatment is 20 mg administered once daily in the evening. Patients with mild to moderate hypercholesterolemia may start with 10 mg and may receive doses of 5 mg to 40 mg once daily. The dosage should be adjusted based on initial LDL levels, treatment goals, and patient response to the medication.

Child dose

The recommended initial dose for pediatric patients (10-17 years) with familial heterozygous hypercholesterolemia is 10 mg once daily in the evening, with a recommended dose range of 10-40 mg and a maximum dose of 40 mg.

This medication can cause serious muscle-related side effects such as myopathy and rhabdomyolysis; therefore, caution is required, especially for patients taking high doses. Patients with impaired liver function or active liver disease, pregnant or nursing women should not take this medication. If symptoms such as liver dysfunction, muscle pain, or muscle weakness occur, inform a doctor immediately, and discontinue the medication if necessary. This medication can interact with various drugs, so inform your physician or pharmacist if you are taking other medications. Avoid concurrent use with strong CYP3A4 inhibitors, gemfibrozil, cyclosporine, danazol, etc., as this increases the risk of myopathy. Elderly patients, those with decreased kidney function, and patients with hypothyroidism should use this medication with caution. Women who are pregnant or may become pregnant must use contraception, and should stop taking the medication if pregnancy is confirmed. This medication contains lactose; patients with lactose intolerance should not take it. During treatment, regular checks of liver function and muscle-related tests are recommended, and consult healthcare providers immediately if any abnormal symptoms occur. Special attention is needed when administering to children and adolescents, and it is not recommended for children under 10 years old. Store this medication out of the reach of children and keep it in its original container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe allergic reaction, severe rash with high fever, blisters, skin peeling, pain in the mouth/eyes mucosa, severe skin adverse reactions, difficulty breathing or shortness of breath, asthma attack, respiratory abnormalities with cough + fever, yellowing of skin or eyes (jaundice), severe malaise, liver abnormalities (jaundice), sudden and severe reactions

Mild side effects

Abdominal pain, weakness, constipation, diarrhea, indigestion, bloating, nausea, headache, upper respiratory infection, atrial fibrillation, gastritis, diabetes, muscle pain, insomnia, dizziness, bronchitis, rhinitis, eczema, urinary tract infection, hair loss, itching, skin changes (nodules, pigmentation, skin/mucous membrane dryness, hair/nail changes), lichenoid drug rash, gynecomastia, decreased libido, sexual dysfunction (including erectile dysfunction), progression of cataracts, ocular muscle paralysis, anemia

Store this medication in a tightly closed container to prevent air and moisture from entering. It is essential to maintain a storage temperature between 1°C and 30°C to ensure the safety and efficacy of the medication.

Appearance

Pink oval film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle