ACEPEN Soft Capsule (Naproxen)

Key information summary

Efficacy & effects

This medication is effective for degenerative joint diseases such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendinitis (tendon inflammation), acute gout, and dysmenorrhea. It can also be used for bursitis, muscle and ligament injuries resulting in sprains or contusions, trauma, low back pain, postoperative pain, migraines, and pain relief after tooth extraction. It shows therapeutic effects for these various conditions and symptoms, helping to alleviate patient discomfort.

Dosage

1. Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis: Naproxen 250-500 mg (1-2 capsules) is taken orally twice a day (every 12 hours). 2. Acute gout: An initial dose of 750 mg (3 capsules) is taken orally, followed by 250 mg (1 capsule) every 8 hours until the attack subsides. 3. Musculoskeletal disorders, postoperative pain, pain after tooth extraction, dysmenorrhea, tendinitis, bursitis: Initial

Precautions

This medication may increase the risk of gastrointestinal bleeding if taken by individuals who regularly consume more than three alcoholic drinks daily; therefore, it is essential to consult with a doctor or pharmacist. This medication can affect the cardiovascular system, potentially leading to severe vascular issues such as myocardial infarction or stroke; individuals with heart diseases or risk factors should exercise particular caution. This medication may cause serious problems such as bleeding, ulcers, or perforations in the stomach and intestines, and older adults are at a higher risk for these complications; therefore, they should monitor for changes in symptoms while taking this medication. Individuals with peptic ulcers, severe blood disorders, very poor liver or kidney function, severe hypertension, or decreased cardiac function should not use this medication. Patients with hypersensitivity or allergies to aspirin or other non-steroidal anti-inflammatory drugs may react sensitively to this drug, requiring caution. If abnormal symptoms such as difficulty breathing, low blood pressure, rash, severe headache, nausea, vomiting, or skin rash occur while taking this medication, it should be discontinued immediately, and a doctor should be consulted. The risk of adverse effects may increase if this medication is taken together with other non-steroidal anti-inflammatory drugs or certain medications; thus, it is crucial to discuss with healthcare professionals. During pregnancy, especially in the later stages, there may be risks to the fetus; women who are pregnant or may become pregnant should consult a doctor before using this medication. This medication can also be transmitted through breast milk, potentially affecting newborns, so breastfeeding women should avoid taking it. The safety of this medication has not been established in children, especially in infants under 2 years of age, so its use should be avoided in this age group. Elderly patients are at higher risk for gastrointestinal bleeding or ulceration, so treatment should start at the minimum dosage while closely monitoring their condition. If this medication is used for an extended period, regular blood tests and liver function tests should be conducted to identify any abnormalities; if any issues are found, the use should be discontinued. In cases of overdose, symptoms such as drowsiness, indigestion, and vomiting may occur; thus, immediate medical attention should be sought.

Side effects

Urticaria, severe swelling, cold sweat, difficulty breathing, hypotension, hematemesis, gastrointestinal bleeding, peptic ulcer, perforation, agranulocytosis, leukopenia, thrombocytopenia, aplastic anemia, hemolytic anemia, platelet dysfunction, jaundice, hepatitis, renal impairment, glomerulonephritis, hematuria, interstitial nephritis, nephrotic syndrome, renal papillary necrosis, proteinuria, renal failure, aseptic meningitis, severe headache, altered consciousness, Stevens-Johnson syndrome, epidermolysis bullosa, eosinophilia

Interactions

Do not take this medication with other non-steroidal anti-inflammatory drugs or naproxen derivatives. Do not combine with hydantoins, sulfa drugs, sulfonylurea-based antihyperglycemic agents, propranolol or other beta-blockers, ACE inhibitors (such as captopril), loop and thiazide diuretics, probenecid, aspirin, lithium, methotrexate, coumarin-based anticoagulants (such as warfarin), zidovudine, or quinolone antibiotics (such as enoxacin).

Alternatives / Same-ingredient medications

• 

  Naxen Tablet (Naproxen)

  Same ingredient
• 

  NACEN F Tablet (Naproxen)

  Same ingredient
• 

  TACEN Soft Capsule (Naproxen)

  Same ingredient
• 

  Aproxen Soft Capsule (Naproxen)

  Same ingredient

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