Cephadil Capsule (Cefadroxil Hydrate)

Adult dose

1) Urinary tract infections: For uncomplicated lower urinary tract infections (such as cystitis), 1-2g (potency) of cephadroxil should be administered orally in 1-2 divided doses per day. For other urinary tract infections, 2g (potency) should be administered in 2 divided doses per day. 2) Skin and soft tissue infections: 1g (potency) should be administered orally in 1-2 divided doses per day. 3) Pharyngitis, tonsillitis: For beta-hemolytic streptococcal infections causing pharyngitis and tonsillitis, 1g (potency) should be administered orally divided into 1-2 doses for 10 days.

Child dose

1) Urinary tract infections, skin and soft tissue infections: Administer 30mg (potency) per kg of body weight orally divided into 2 doses per day. 2) Pharyngitis, tonsillitis: Administer 30mg (potency) per kg of body weight orally divided into 1 to 2 doses per day.

This medication should not be used in patients who have experienced severe allergic reactions or shock from this medication in the past. It should also not be administered to patients who have had allergic reactions to cephalosporin antibiotics or those with infectious mononucleosis. In patients with a history of hypersensitivity, it is generally not recommended, but if absolutely necessary, it should be administered with extreme caution. Patients allergic to penicillin antibiotics or those with a family history of easily developing allergic symptoms should also be cautious. Patients with severely compromised renal function, those unable to take orally, elderly patients, and patients in poor general condition should be monitored closely as they may show signs of vitamin K deficiency. Patients with gastrointestinal disorders, especially those with a history of colitis, should also use this medication with caution. Rarely, shock or severe allergic reactions may occur while using this medication; therefore, if any unusual symptoms appear, administration should be stopped immediately and appropriate treatment should be administered. Changes in blood cell counts, hepatic dysfunction, renal impairment, severe colitis, respiratory issues, stomatitis, neurological symptoms, etc., can occur, so symptoms should be monitored carefully. Severe skin reactions may especially occur, so the condition of the skin should be monitored, and signs of vitamin deficiency may also rarely occur. To prevent the emergence of resistant bacteria, it is recommended to determine the susceptibility of the infecting organism and use this medication for only the minimum necessary duration. Due to the risk of hypersensitivity, a thorough medical history investigation is needed before administration, and if an allergic reaction occurs, the medication should be stopped immediately and appropriate treatment should be given. With long-term use, regular tests of blood, renal, and hepatic function should be conducted to check for abnormalities. In patients with decreased renal function, dosage adjustments may be necessary, and caution is needed as neurological side effects such as seizures may occur. When used with other nephrotoxic drugs or diuretics, the risk of renal damage may increase, so caution should be exercised. Additionally, certain medications may increase the plasma concentration of this drug, so caution is warranted. Women who are pregnant or capable of becoming pregnant should only use this medication when the benefits of treatment outweigh the risks, as its safety has not been established. Breastfeeding women should also be cautious when using this medication. Elderly patients may experience abnormal reactions more easily due to decreased body function, and the risk of bleeding related to vitamin K deficiency may also increase, so dosage and administration interval should be adjusted carefully. This medication may also affect the results of certain clinical tests, so caution should be taken when interpreting test results. Lastly, sensitivity to light may increase while using this medication, so it is advisable to avoid sun exposure.

Serious side effects

Hives, shock, anaphylaxis (severe allergic reaction), severe colitis with bloody stools, difficulty breathing, interstitial pneumonia, eosinophilic pulmonary infiltration, Stevens-Johnson syndrome, seizures, severe renal impairment (acute renal failure), severe edema, elevation of blood pressure, bleeding tendency (related to vitamin K deficiency), severe allergic reactions, severe skin reactions, respiratory issues, hepatic abnormalities (jaundice), severe neurological symptoms, severe edema or abdomen

Mild side effects

• Rash
• facial swelling
• angioedema
• mucosal blistering
• itching
• fever
• thrombocytopenia
• granulocytopenia
• agranulocytosis
• eosinophilia

This medication should be stored in a tightly sealed container to prevent air from entering, and it is best to store it at room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain the medication's effectiveness and prevents degradation.

Appearance

A hard capsule containing a crystalline powder that is white to pale yellow in color with a green upper part and a light green lower part

Package unit

30 capsules/bottle, 500 capsules/bottle