Uninapin Tablets (Terbinafine Hydrochloride)

Adult dosage

For Terbinafine: 125 mg twice daily or 250 mg once daily. The duration of treatment depending on the disease is as follows: 1) Dermatophyte infections Tinea Pedis (interdigital type, plantar type/moccasin type): 2–6 weeks Tinea Corporis: 2–4 weeks Tinea Cruris: 2–4 weeks 2) Onychomycosis Typically administered for 6 weeks to 3 months. If the infection is in the fingernails or relatively small toes, or for younger patients, the treatment duration may be shortened to less than 3 months. The treatment duration for toenail infections is usually sufficient at 3 months, but some patients may take 6 months or longer. In cases where the nail growth rate is slow, the treatment period may be extended.

Children's dosage

Administered to children over 2 years of age. Tinea Capitis: 4 weeks 1) In children weighing less than 20 kg (under 5 years old): 62.5 mg once daily. Due to the lack of treatment experience, the benefits and risks of treatment should be considered.

This medication is not recommended for patients with liver problems or a history of liver disease. Liver function tests should be performed before use, and liver function should be monitored regularly during treatment. If symptoms of liver dysfunction occur, discontinue use immediately and consult a doctor. This medication should not be used in patients with severe blood disorders or significantly impaired kidney function, children under 2 years of age, or nursing mothers. Additionally, individuals with allergies to this medication should not take it. Special caution is required for elderly patients or children with low body weight when using this medication. If severe skin rash or allergic reactions occur, discontinue use immediately. This medication is primarily metabolized in the liver, so individuals with weak liver or kidney function should use it after consulting a doctor. Dizziness or drowsiness may occur while taking this medication, so it is advisable to avoid driving or operating machinery. There may be interactions with other medications, so if you are taking other medications, be sure to inform your doctor or pharmacist. Women who are pregnant or may become pregnant should thoroughly consult with their doctor regarding the use of this medication, and nursing mothers should avoid taking it. Overdose may result in headaches, nausea, abdominal pain, and dizziness, and if these symptoms occur, seek medical attention immediately. This medication should be stored out of the reach of children, protected from direct sunlight, and kept at room temperature.

Serious side effects

Cholestatic hepatitis, hepatitis, cholestasis, jaundice, neutropenia, pancytopenia, agranulocytosis, thrombocytopenia, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute kidney injury accompanied by rhabdomyolysis, respiratory distress, chest tightness, urticaria, anaphylactic reactions (including angioedema, superficial and systemic lupus erythematosus), paralysis, severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis)

Mild side effects

Rash, skin itching, fever, nausea, vomiting, loss of appetite, malaise, leukopenia, anemia, photosensitivity reactions, acute generalized exanthematous pustulosis, erythema multiforme, toxic skin reactions, exfoliative dermatitis, vesicular dermatitis, psoriasiform rash or worsening of psoriasis, hair loss, musculoskeletal reactions (arthralgia, myalgia), muscle pain, weakness, elevated CPK, increased myoglobin in blood and urine, hypotension, erythema, facial edema, lymphangiectasia, abdominal discomfort

This medication should be stored in a sealed container to prevent air or moisture from entering, and it is recommended to keep it at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain its effectiveness for a longer period.

Appearance

White to whitish round tablets

Package unit

In-house packaging unit