Ranitid Tablet (Ranitidine Hydrochloride)

Adult dose

As ranitidine, the dosing for adults is 150 mg once, twice a day, taken orally in the morning and at bedtime. For gastric and duodenal ulcers, it can be taken as 150 mg twice a day or 300 mg once a day before bedtime. The treatment rate for duodenal ulcer patients can be significantly higher when taking 300 mg twice daily. The same dosage refers to the prevention of ulcers caused by NSAID use.

Child dose

For children aged 8 to 18 years, the dosage can be 150 mg (2 mg per kg of body weight) once per dose, up to 2 doses a day.

This medication should not be used in patients with a history of hypersensitivity to any component of this drug or a history of acute porphyria. Patients with impaired renal function may have increased blood concentration of this medication since it is excreted through the kidneys; therefore, the dosage should be reduced or the dosing interval extended. Patients with impaired liver function, a history of drug hypersensitivity, and elderly patients should also use it with caution. Patients taking nonsteroidal anti-inflammatory drugs should be monitored regularly. This medication may mask symptoms of gastric cancer, so patients with gastric ulcers or middle-aged patients with new dyspeptic symptoms should verify malignancy before usage. Patients with gastric and duodenal ulcers caused by Helicobacter pylori need concurrent therapy to eradicate the bacteria. Rarely, shock or allergic reactions, blood abnormalities, liver dysfunction, cardiac rhythm disturbances, gastrointestinal symptoms, and psychiatric symptoms may occur while taking this medication; if these symptoms arise, use should be discontinued immediately and a doctor consulted. Regular blood tests and liver and kidney function tests should be performed to confirm normality during treatment. The risk of pneumonia may be increased in the elderly, patients with chronic diseases, and those with weakened immune systems. If dizziness or drowsiness occurs after taking this medication, avoid driving or operating hazardous machinery. There may be interactions with other medications; careful monitoring of blood coagulation status is required, especially in patients taking anticoagulants like warfarin. When taking with drugs such as sucralfate, dosing should be spaced at least 2 hours apart as it may interfere with absorption. Women who are pregnant or potentially pregnant and nursing mothers should carefully weigh the benefits and risks before using this medication. Safety for use in children has not been adequately confirmed; caution is needed. Elderly patients may have increased medication concentrations due to decreased kidney function; therefore, dosage adjustment may be necessary. Some tests may yield false-positive results due to this medication, so care should be taken with testing methods. In case of overdose, gastric lavage or appropriate treatment is required, and in severe cases, blood dialysis may be needed. Store out of reach of children and do not transfer medication to other containers for safety.

Serious side effects

• Hives
• angioedema
• chest pain
• shock
• anaphylactic shock
• bronchospasm
• hypotension
• jaundice
• hepatitis
• altered consciousness

Mild side effects

• Increased serum creatinine levels
• constipation
• nausea
• vomiting
• abdominal bloating
• abdominal pain
• loss of appetite
• diarrhea
• dizziness
• drowsiness

This medication is sensitive to light, so it should be stored in a container that protects it from light. Additionally, it is important to store it at room temperature between 1°C and 30°C. This will help maintain the effectiveness of the medication and ensure safe usage.

Appearance

Cream to pale yellow round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle, 300 tablets/bottle