Bast Tablet 20 Milligrams (Simvastatin)

Adult dose

It is recommended to administer 5 to 40 mg once daily in the evening for this medication. The initial starting dose is 20 mg daily, and for patients at high risk for cardiovascular disease, 40 mg daily is administered. Dose adjustment is required for certain patient populations (the elderly, those with renal impairment, patients taking certain drugs), with a maximum dose of 80 mg daily.

Child dose

For pediatric patients aged 10 to 17 years, administer 10 mg once daily in the evening, with a recommended dosage range of 10 to 40 mg daily, and a maximum of 40 mg daily. When adjusting the dosage, allow for intervals of at least 4 weeks.

This medication can cause muscle disorders such as myopathy or rhabdomyolysis, especially at high doses. Therefore, patients taking this medication at high doses should immediately consult a doctor if they experience muscle pain or weakness. Patients with an allergy to this medication, those with active liver disease, pregnant women or women of childbearing potential, and patients taking certain medications should not use this medication. Patients with impaired liver or kidney function, those with hypothyroidism, the elderly, and women should exercise additional caution when using this medication. This medication can affect liver function; therefore, regular liver function tests and blood tests are necessary, and if any symptoms of liver abnormalities appear, use should be discontinued immediately. As this medication interacts with other drugs, the risk of muscle damage may increase, especially when taken with certain antifungals, antibiotics, immunosuppressants, or some heart medications, so it is crucial to inform the doctor or pharmacist about all current medications. Grapefruit juice should be avoided as it may increase the blood concentration of this medication, raising the risk of side effects. Pregnant or breastfeeding women should not take this medication, and women who are of childbearing age should ensure adequate contraception while taking it. Children and adolescents can only use this medication beyond a certain age, so they must follow a doctor's instructions. In case of overdose, seek medical attention immediately for appropriate treatment, and this medication should be kept out of the reach of children.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough + fever, yellowing of skin or eyes (jaundice), severe lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination.

Mild side effects

Muscle pain, muscle cramps, joint pain, constipation, diarrhea, dyspepsia, bloating, nausea, headache, weakness, upper respiratory infection, gastritis, insomnia, dizziness, bronchitis, sinusitis, eczema, urinary tract infection, alopecia, itching, skin/mucosal dryness, hair/nail changes, flat patch-like drug rash, gynecomastia, decreased libido, sexual dysfunction (including erectile dysfunction), progression of cataracts, ocular muscle paralysis, anemia, thyroid dysfunction, serum creatinine.

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is recommended to maintain a storage temperature between 1°C and 30°C at room temperature. Proper storage will help maintain the safety and effectiveness of the medication.

Appearance

Brownish-yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle