Cecil Pro Dry Syrup 125mg/5mL (Cefprozil Hydrate)

Adult dose

○ Adults (13 years and older) 1) For pharyngitis and tonsillitis among upper respiratory tract infections, administer cefprozil 500mg (potency) per dose every 24 hours; for acute sinusitis, administer 250mg (potency) or 500mg (potency) every 12 hours (an increased dose is required for moderate or more severe infections). 2) For bacterial superinfection of acute bronchitis or bacterial exacerbation of chronic bronchitis among lower respiratory tract infections, administer 500mg (potency) of this drug per dose every 12 hours. 3) For uncomplicated skin and soft tissue infections, administer 250mg (potency) of this drug per dose every 12 hours [or 500mg (potency) every 24 hours], or administer 500mg (potency) every 12 hours according to symptoms. 4) For uncomplicated urinary tract infections, administer 500mg (potency) of this drug every 24 hours. <Duration of treatment> Treatment is generally administered for about 10 days; however, for pharyngitis/tonsillitis caused by Streptococcus pyogenes (Group A beta-hemolytic), administer for 10 days or longer. For uncomplicated cystitis, administer for about 7 days. ○ Patients with renal impairment 1) If creatinine clearance is 30～120mL/min, administer according to the standard dosage and administration above. 2) If creatinine clearance is 29mL/min or less, administer 50% of the standard dose, using the same dosing interval as the standard regimen. However, some of this drug is removed by hemodialysis, so administer it after hemodialysis is completed. Once reconstituted, store refrigerated and use within 14 days (syrup only).

Child dose

○ Children (2～12 years) 2～12 years: For pharyngitis and tonsillitis among upper respiratory tract infections, administer 7.5mg (potency) per Kg of body weight per dose every 12 hours. 2～12 years: For uncomplicated skin and soft tissue infections, administer 20mg (potency) per Kg of body weight per dose every 24 hours. ○ Infants and children (6 months～12 years) 6 months～12 years: For otitis media among upper respiratory tract infections, administer 15mg per Kg of body weight every 12 hours, 6 months～12 years: For acute sinusitis, administer 7.5mg per Kg of body weight every 12 hours. 6 months～12 years: For moderate or more severe infections requiring an increased dose, administer 15mg per Kg of body weight every 12 hours.

This medication contains the artificial sweetener aspartame, which is broken down into phenylalanine in the body; therefore, patients with the genetic condition phenylketonuria should not take this medication. Patients with a history of allergic reactions to cephalosporin antibiotics should also avoid this medication. Caution is needed in patients with a history of allergies to penicillin or other drugs, especially due to the potential for cross-reactivity with beta-lactam antibiotics. In patients with renal function decline or suspected renal impairment, the dosage of this medication should be reduced and monitored carefully. Patients with a history of gastrointestinal diseases, especially colitis, should use this medication with caution. This medicine contains Yellow No. 5 as a coloring agent; patients with allergies to this ingredient should take it carefully. Taking this medication may cause gastrointestinal side effects such as diarrhea, nausea, vomiting, and abdominal pain, and liver function tests may show elevated levels. Rarely, allergic reactions such as rash or hives, as well as central nervous system symptoms like dizziness, headaches, and drowsiness may occur. In patients with renal impairment, seizures may occur, so if such symptoms appear, the medication should be discontinued immediately. When taken with other antibiotics or diuretics, the risk of renal toxicity may increase, so inform your healthcare provider. Pregnant or breastfeeding women should only use this medication when necessary, and special care should be taken during breastfeeding as the effects on the infant are unknown. It is advised not to use this medication in infants under 6 months old due to not having confirmed safety and efficacy. In the elderly, dosage adjustments may be necessary considering the risk of decreased renal function. If diarrhea occurs while using the antibiotic, the possibility of pseudomembranous colitis should be suspected, and medical consultation should be sought immediately. In the case of overdose, the medication is excreted through the kidneys, so patients with renal impairment may require hemodialysis. This medication may affect the results of blood tests or urine tests, so inform your healthcare provider before the tests.

• Diarrhea
• nausea
• vomiting
• abdominal pain
• elevated AST
• elevated ALT
• elevated ALP
• elevated bilirubin levels
• rash
• urticaria

This medication should be stored in a container that blocks light and air, ideally at room temperature between 1 degree and 30 degrees Celsius. Storing it this way will help maintain the medication's effectiveness for a longer duration.

Appearance

Whitish to pale yellow powdered syrup

Package unit

30 grams/bottle [60 milliliters/bottle]