Lisinopril Tablets (Clarithromycin)

Adult dose

○ Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7～14 days. In patients with renal failure whose creatinine clearance is 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer this medicine to such patients for more than 14 days. ○ Mycobacterial infections: Administer 500mg (potency) twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine three times daily for 14 days in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) three times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Child dose

Children aged 12 years and older: same as adults For children under 12 years, use clarithromycin dry syrup.

This medication should not be administered to certain patients. For example, patients allergic to any of the ingredients in this medication or who have had hypersensitivity reactions to similar antibiotics should not take it. Additionally, patients taking specific drugs that may affect heart rhythm, or those with severely impaired liver or kidney function should not be given this medication. It is also safest for pregnant or breastfeeding women to avoid using it. This medication should be used cautiously for patients with impaired liver or kidney function, heart disease, elderly patients, and those taking other specific antibiotics or medications. Especially, patients with drug allergies or sensitivity to colorants in this medication should use it carefully. While taking this medication, serious allergic reactions, gastrointestinal disturbances, liver or kidney dysfunction, skin rashes, neurological symptoms, etc., may rarely occur, and if such symptoms arise, a doctor should be consulted immediately. This medication may cause hearing impairment or tinnitus with prolonged use or overdose, and it is essential to adhere to the prescribed duration and dosage to prevent the emergence of resistant bacteria. Additionally, due to numerous drug interactions, any concurrent medications should be reported to a doctor or pharmacist. Pregnant or breastfeeding women should avoid this medication and should be administered with caution to children according to their age and condition. Elderly patients may require dosage adjustments due to potential increases in drug concentration from impaired renal function. In cases of overdose, gastrointestinal disturbances or psychological symptoms may occur, thus it is important to adhere to the prescribed dosage and visit a hospital immediately if any abnormal symptoms arise. This medication should be stored at room temperature and kept away from direct sunlight. Refrigeration is not necessary.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rash, itching, hives, skin erythema, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, indigestion, abdominal pain, discomfort, bloating, diarrhea, oral mucosal erosion, upper abdominal pain, dry mouth, transient tooth discoloration, pancreatitis, increased amylase, dysgeusia, decreased appetite, constipation, stool discoloration, pseudomembranous colitis, hemorrhagic colitis, fever, cough, chest X-ray abnormalities, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, decreased appetite, jaundice, dark urine, pruritus, abdominal tenderness, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, myalgia, weakness, elevated CPK, increased serum myoglobin, increased urinary myoglobin, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, dysgeusia, auditory loss, paresthesia, arthralgia, myalgia, olfactory dysfunction, tinnitus, hearing impairment, hypoglycemia, tinnitus, hearing loss, vomiting, nausea, abdominal pain, purpuric rash, acute generalized exanthematous pustulosis, soft tissue infection, candidiasis, gastroenteritis, infection, vaginal infection, leukopenia, neutropenia, thrombocytosis, agranulocytosis, thrombocytopenia, anaphylactoid reaction, angioedema, decreased appetite, insomnia, neuroexcitation, noise discharge, psychotic disorder, confused state, abnormal dreams, movement disorders, non-vestibular dizziness, drowsiness, tremors, vestibular dizziness, auditory impairment, hearing loss, cardiac arrest, atrial fibrillation, ectopic beats, palpitations, vasodilation, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, liver function test abnormalities, bile stasis, increased alanine aminotransferase, increased aspartate aminotransferase, increased gamma-glutamyl transferase, hepatocellular jaundice, vesicular dermatitis, hyperhidrosis, papular rash, acne, Henoch-Schonlein purpura, muscle cramps, musculoskeletal rigidity, myopathy, nephritis, injection site thrombophlebitis, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, urine discoloration

This medication is light-sensitive and should be stored in a tightly sealed container that is not exposed to light. Additionally, it is important to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature. Proper storage will help preserve the drug's efficacy and safety.

Appearance

Yellow oval film-coated tablets with a vanilla scent

Package unit

30 tablets, 100 tablets/bottle