Simvast Tablets 40 mg (Simvastatin)

Adult dose

1. Reduction of cardiovascular disease risk: The recommended starting dose is 40 mg once daily. 2. Hyperlipidemia: - The usual starting dose is 20 mg once daily in the evening. - Patients with mild to moderate hypercholesterolemia may start with 10 mg. - 5 to 40 mg once daily in the evening is recommended. - Patients with heterozygous familial hypercholesterolemia may receive 1 daily dose of

Child dose

Children with heterozygous familial hypercholesterolemia (ages 10 to 17): The recommended starting dose is 10 mg once daily in the evening. The recommended dosage range is 10 to 40 mg daily, with a maximum dose of 1

This medication may cause muscle-related side effects such as myopathy or rhabdomyolysis, so caution is advised, especially when taking high doses. Patients with an allergy to this medication or its ingredients, those with liver dysfunction, pregnant or breastfeeding women, and those taking certain medications should not take this drug. Patients with impaired liver function or kidney issues, those with hypothyroidism or a history of muscle disorders, elderly patients, and women should use this medication with care. If muscle pain, muscle weakness, or unexplained muscle soreness occurs during treatment, consult your physician immediately, as discontinuation may be necessary in some cases. Since this medication is metabolized in the liver, patients with liver dysfunction should undergo regular liver function tests, and those with a history of liver disease should be particularly cautious. This medication may interact with multiple drugs, so inform your physician or pharmacist if you are taking other medications, especially when combined with certain antifungals, antibiotics, immunosuppressants, calcium channel blockers, or niacin. Women who are pregnant or may become pregnant should not take this medication, and if pregnancy occurs during treatment, it should be stopped immediately, and a physician should be consulted. This drug is also used in children and adolescents, but safety in children under 10 has not been established, hence it should not be administered to this age group. Elderly patients may have higher blood levels of this medication, necessitating dosage adjustments and careful monitoring. In case of overdose, specific antidotes are not available; general treatment is required, and this medication should be stored out of reach of children and kept in its original container.

Serious side effects

Hives, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweats, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, jaundice (yellowing of skin or eyes), generalized malaise, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination problems

Mild side effects

• Abdominal pain
• weakness
• constipation
• diarrhea
• dyspepsia
• bloating
• nausea
• headache
• upper respiratory tract infection
• atrial fibrillation

This medication should be stored in a tightly closed container to protect it from air and moisture. It is recommended to keep the storage temperature between 1 and 30 degrees Celsius.

Appearance

Oval film-coated tablet of red brick color

Package unit

30 tablets/bottle