NewGen Pharm Cefuroxime Tablet (Cefuroxime Axetil)

Adult dose

For optimal absorption, take after meals. Adults and children 12 years and older Most infections: Administer 250mg twice daily. Severe lower respiratory tract infections, pneumonia, severe infections, or suspected infections caused by less susceptible bacteria: Administer 500mg twice daily. Urinary tract infections: Administer 250mg twice daily. Uncomplicated gonorrhea: Administer 1g as a single dose. Lyme disease: Administer 500mg twice daily for 14 days (10~21 days). For the treatment of infections caused by Streptococcus pyogenes (Group A beta-hemolytic), this drug should be administered for 7~10 days. 3. Patients with renal impairment Cefuroxime is primarily excreted by the kidneys. To compensate for delayed excretion in patients with significantly impaired renal function, cefuroxime doses should be reduced as follows. ≥ 30 mL/min/1.73m2: No dose adjustment required (standard dose: 125mg-500mg twice daily) 10 - 29 mL/min/1.73m2: Administer a standard single dose every 24 hours < 10 mL/min/1.73m2: Administer a standard single dose every 48 hours Patients on hemodialysis: Administer an additional standard single dose at the end of each dialysis session

Child dose

Children under 12 years of age, most infections: Administer 125mg twice daily. Children 2 years of age and older, otitis media or severe infections: Administer 250mg twice daily. Children under 12 years of age, Lyme disease: Administer 250mg twice daily for 14 days (10~21 days). Infants under 3 months of age: There is insufficient experience with use. Not suitable for the treatment of patients who cannot swallow tablets, such as young infants and children.

This medication is a cephalosporin antibiotic and should not be used in patients with allergies to this class of drugs. Caution should be exercised when administering to patients with a history of allergy to penicillins or other beta-lactam antibiotics, allergic patients, patients with severe renal impairment, elderly patients, or those unable to take oral medication. Mild and transient side effects are common, with frequent adverse effects including headache, dizziness, diarrhea, nausea, and abdominal pain. Rarely, skin rashes, urticaria, itching, liver dysfunction, renal impairment, and severe skin reactions may occur, so if any unusual symptoms appear, immediate consultation with a physician is essential. During antibiotic use, there may be excessive proliferation of Candida species, and a decrease in beneficial intestinal bacteria could lead to diarrhea or pseudomembranous colitis; therefore, caution is necessary. This medication may induce dizziness while driving or operating machinery, so caution should be exercised. Women who are pregnant or breastfeeding should consult a physician before taking this medication, as its safety has not been established. Safety has not been verified for infants under 3 months old, and when administering to children, due to taste issues, it may be advisable to substitute with syrup formulations. Elderly patients may have increased bleeding risks due to renal impairment and vitamin K deficiency, so careful adjustment of dosage and intervals is necessary. This medication may affect some clinical test results, so it is important to inform healthcare personnel during testing. In case of overdose, central nervous system side effects such as seizures may occur, and blood dialysis or peritoneal dialysis can be used to reduce drug concentration. This medication should be kept out of reach of children and stored sealed in its original container to maintain quality.

• Candida overgrowth
• eosinophilia
• positive Coombs test
• thrombocytopenia
• leukopenia
• granulocytopenia
• anemia
• decrease in hemoglobin
• decrease in hematocrit
• hemolytic anemia

This medication should be stored in a tightly closed container in a cool place below 25 degrees Celsius. Proper storage will help maintain the drug's effectiveness and prevent degradation.

Appearance

White to off-white oblong film-coated tablet

Package unit

- - 100 Tablets/PTP [10 Tablets/PTP x 10]