Medication info
Ciprofloxacin Tablets 100 mg

Ciprofloxacin Tablets 100 mg

Prescription medicationTabletOral
Ingredient · strength
Ofloxacin›100mg / 1 tablet
Manufacturer / importer
Celix Co., Ltd.
Appearance
White round film-coated tablet
Packaging
30 tablets/bottle, 500 tablets/bottle
Approval status
Active

MFDS item code 200401862 · Notified 2004.07.08 · Insurance code 646200420

Summary

Main use
Treatment of genitourinary and intestinal infections, respiratory, ear, nose, skin, and eye infections, and leprosy in combination with other treatments
Who takes it
Adults
Adult dose
The usual adult dosage of ofloxacin is 300~600 mg per day in 2~3 divided doses. For leprosy, the dosage of this medicine is 400~600 mg per day in 2~3 divided doses. In principle, it should be used in combination with other anti-leprosy medicines. The dosage may be adjusted as appropriate according to the patient's age and symptoms.

Ingredients

Manufacturer
Celix Co., Ltd.

Efficacy & effects

Treatment of genitourinary and intestinal infections, respiratory, ear, nose, skin, and eye infections, and leprosy in combination with other treatments

  • Complicated skin and soft tissue infections
  • acute otitis media
  • chronic suppurative otitis media
  • acute and chronic bacterial sinusitis
  • community-acquired pneumonia
  • acute exacerbations of chronic obstructive pulmonary disease including chronic bronchitis
  • acute pyelonephritis
  • uncomplicated acute cystitis
  • bacterial prostatitis
  • epididymitis
  • gonococcal urethritis
  • non-gonococcal urethritis
View approved original text

This medication is a fluoroquinolone antibiotic effective against various bacterial infections, acting on several harmful species including Staphylococcus, Escherichia coli, Pseudomonas aeruginosa, and Haemophilus influenzae. It is primarily used for complicated skin and soft tissue infections, acute and chronic otitis media, acute and chronic sinusitis, community-acquired pneumonia, acute exacerbations of chronic obstructive pulmonary disease, urinary tract infections (acute pyelonephritis, cystitis, prostatitis, urethritis, etc.), bacterial dysentery and enteritis, inflammation of the uterus and appendages in women, and ophthalmic diseases (blepharitis, stye, corneal ulcer, etc.). This medication is particularly selected in cases where existing treatments are difficult due to chronic conditions or acute situations, and is included in combination therapy for leprosy. Due to the risk of serious adverse reactions associated with fluoroquinolone medications, it is important to use this medication only under the guidance of a physician when necessary. Patients can benefit from the treatment of various infections using this medication.

How to take

Adult dose

The usual adult dosage of ofloxacin is 300~600 mg per day in 2~3 divided doses. For leprosy, the dosage of this medicine is 400~600 mg per day in 2~3 divided doses. In principle, it should be used in combination with other anti-leprosy medicines. The dosage may be adjusted as appropriate according to the patient's age and symptoms.

Precautions

This medication is a fluoroquinolone antibiotic used for the treatment of bacterial infections. Precautions should be taken as serious side effects related to tendons, such as tendonitis or tendon rupture, may occur while using this medication. Additionally, it may affect the central nervous system, causing symptoms such as headaches, dizziness, and seizures, and should not be administered to patients with myasthenia gravis as it may worsen symptoms. This medication is only used when there are no alternative treatments for specific infections such as acute bacterial sinusitis, acute exacerbations of chronic bronchitis, uncomplicated urinary tract infections, and acute otitis media. Elderly patients, those with impaired kidney function, and patients using corticosteroids should be particularly cautious as the risk of tendon rupture is increased. Various side effects can occur, including allergic reactions, liver and kidney dysfunction, gastrointestinal disorders, blood disorders, neurological and psychiatric disorders, skin rashes; therefore, patients should immediately inform healthcare providers of any unusual symptoms. Particularly, serious allergic reactions, including anaphylaxis, can occur infrequently, and if symptoms such as hypotension, difficulty breathing, or chest tightness appear during administration, the medication should be stopped immediately. This medication should not be administered to patients with specific genetic disorders, a history of seizures, women who are pregnant or breastfeeding, or adolescents under 18 years of age. It may also interact with other medications, therefore it is important to inform healthcare providers of any medications being taken, such as warfarin, antidiabetic agents, or antacids, and to maintain a time interval when taking this medication concurrently. Adequate hydration is necessary during administration and excessive exposure to sunlight should be avoided. Visual disturbances or peripheral neuropathy may occur as side effects; should these symptoms arise, immediate consultation with an ophthalmologist is advised. Elderly patients may experience elevated drug concentrations due to decreased renal function, thus requiring dose adjustment and careful monitoring. Finally, adverse effects on joints have been reported in young animals, thus this medication should not be used in growing children and adolescents.

Side effects

Tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects, exacerbation of myasthenia gravis, anaphylactic shock, anaphylactoid reactions, rash, itching, erythema, edema, fever, warmth, photosensitivity reaction, hematuria, acute kidney failure, nephrolithiasis, interstitial nephritis, increased BUN, elevated serum creatinine, jaundice, liver failure, elevated AST/ALT, increased ALP, elevated γ-GTP, increased total bilirubin, cholestatic jaundice, fulminant hepatitis, membranous colitis, abdominal pain, diarrhea, nausea, vomiting, gastric and abdominal discomfort, cirrhosis, loss of appetite, epigastric pain, dyspepsia, chest pain, thirst, taste disturbance, stomatitis, glossitis, abdominal distension, constipation, dysphagia, gastrointestinal bleeding, oral mucosal pain, intestinal perforation, anemia, leukopenia, decreased hemoglobin, decreased hematocrit, thrombocytopenia, eosinophilia, agranulocytosis, thrombotic thrombocytopenic purpura, petechiae and purpura, prolonged prothrombin time, reversible bone marrow suppression, lymphopenia, neutropenia, increased ESR, insomnia, dizziness, headache, convulsions, tremors, paresthesia, peripheral nerve disorders, visual disturbances, auditory disturbances, hallucinations, drowsiness, neurogenic irritability, sleep disorders, confusion, anxiety, depression, agitation, hypomania, delirium, suicidal ideation, suicide, perceptual disturbances, olfactory and vestibular sensory disorders, ataxia, aphasia, heaviness of the head, skin and mucous membrane syndrome, toxic epidermal necrolysis, arthralgia, myalgia, muscle weakness, myositis, rhabdomyolysis, pharyngitis, dyspnea, bronchospasm, allergic pneumonia, epistaxis, stridor, fever, cough, interstitial pneumonia, cerebral thrombosis, pulmonary edema, tachycardia, hypertension, hypotension, palpitations, vasodilation, circulatory collapse, QT prolongation, ventricular tachycardia, dysuria, frequent urination, urinary retention, anuria, polyuria, hematuria, storage urine, pyuria, diabetes, proteinuria, alkaline urine, vaginitis, vulvovaginal candidiasis, increased vaginal discharge, pruritus of the female external genitalia, menstrual irregularities, uterine cramps, eruption of female genitalia, pain, irritation, burning sensation, symptoms of hypoglycemia, limb pain, lethargy, fever, aortic aneurysm, aortic dissection, cardiac valve regurgitation, cardiac valve insufficiency

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air ingress. The storage temperature should be maintained between 1 and 30 degrees Celsius.

Appearance and packaging

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.