Domperin Tablets (Domperidone Maleate)

Adult dose

In general, do not use for more than 1 week.

Child dose

Adults and adolescents (12 years and older, weighing 35kg or more): Administer 10mg of domperidone (5mg when levodopa is administered) orally 3 times daily before meals. The maximum daily dose is 30mg.

This medication should not be used in patients who have an allergy or have experienced hypersensitivity reactions to the ingredients of this medication. In patients with gastrointestinal issues such as gastrointestinal bleeding, mechanical obstruction, or perforation, the prokinetic effect of this medication may pose risks, so it should not be administered. Patients with prolactin-secreting tumors are advised not to use this medication, as it can promote prolactin secretion. Patients taking strong CYP3A4 enzyme inhibitors should not use this medication in conjunction with it, as it may increase drug concentrations and the risk of side effects. Patients taking medications that cause cardiac conduction abnormalities, patients with prolonged QTc interval, patients with electrolyte imbalances, and heart failure patients are contraindicated to use this medication, as it may exacerbate heart problems. Patients with moderate to severe liver dysfunction, pregnant women, or women who may become pregnant should not take this medication. Patients with genetic metabolic disorders such as lactose intolerance or galactose intolerance should avoid certain formulations of this medication. Caution should be taken when administering to children, especially those weighing less than 35kg, as overdose may lead to neurological symptoms. Patients with kidney disabilities or mild liver dysfunction, elderly patients, and those with a history of heart disease may experience stronger adverse reactions when taking this medication; thus, caution is needed. Since this medication is primarily metabolized in the liver, patients with liver damage should adjust doses or administer carefully. There is a risk of cardiac arrhythmia, so drowsiness or dizziness may occur after taking this medication; it is advisable to avoid driving or operating machinery. This medication has many drug interactions, so the risk of side effects may increase when taken with certain antibiotics, antifungals, and antiarrhythmics; it is essential to consult a doctor. Pregnant or breastfeeding women should avoid taking this medication as it may affect the fetus or newborn; consultation with a doctor is advised. In case of overdose, there is a risk of neurological symptoms and heart problems, so prompt medical attention must be sought for appropriate treatment. This medication should be stored out of the reach of children and kept in its original container to prevent misuse or deterioration.

• Dyspepsia
• gastroesophageal reflux disease
• irritable bowel syndrome
• nausea
• vomiting
• dry mouth
• loss of libido
• anxiety
• drowsiness
• headache

This medication should be stored in an airtight container with good air ventilation, preferably at room temperature between 1 to 30 degrees Celsius. Storing in this way can help maintain the effectiveness of the medication.

Appearance

White round tablets

Package unit

30 tablets/bottle, 1000 tablets/bottle