Ogmex Duo Tablet 500 mg

Adult dose

For severe infections and respiratory infections in adults, take 2 tablets orally, twice daily every 12 hours. In patients with renal insufficiency, dosage may be reduced based on the degree of renal function. This drug should not be administered to patients with severe renal impairment (glomerular filtration rate less than 30 mL/min).

This drug is a beta-lactam antibiotic and should not be used in patients with allergies to penicillin or cephalosporin drugs. In particular, patients with concomitant viral diseases such as infectious mononucleosis or lymphocytic leukemia may have a higher risk of rash when taking this medication. Patients with liver dysfunction or a history of liver impairment or jaundice due to this drug or penicillin should use this medication cautiously due to the risk of recurrence of symptoms. This drug contains lactose, so patients with lactose intolerance or specific genetic metabolic disorders should not take it. Patients with impaired liver function should be cautious as this drug may worsen liver function, and patients with moderate or severe renal impairment should adjust the dosing interval. Patients with an allergic constitution or frequent symptoms such as bronchial asthma, rashes, and hives need to use this medication carefully. Patients who have difficulty swallowing orally, the elderly, or those in poor overall condition should be monitored for symptoms of vitamin K deficiency. In cases of gastrointestinal diseases accompanied by vomiting or diarrhea, drug absorption may not be sufficient. This drug can cause various side effects in the gastrointestinal tract, such as diarrhea, gastritis, vomiting, and abdominal pain, and in severe cases, serious conditions such as pseudomembranous colitis may occur, necessitating immediate discontinuation upon onset of symptoms. Abnormal liver function has also been reported, especially in the elderly or males, and hepatitis or jaundice may occur, so liver function tests are necessary for long-term administration. Rarely, severe skin reactions or hypersensitivity reactions such as anaphylaxis may occur, and if symptoms such as rash, itching, or difficulty breathing arise, the medication should be discontinued immediately, and medical attention should be sought. Blood system abnormalities have also been rarely reported, such as leukopenia, anemia, and thrombocytopenia, so monitoring of symptoms is necessary. Central nervous system abnormalities, such as anxiety, restlessness, drowsiness, and seizures, can occur rarely, and patients with renal impairment are at risk for kidney damage, necessitating regular check-ups. Furthermore, this medication can affect intestinal flora, leading to shifts such as candidiasis or stomatitis. There may be a tendency for bleeding due to vitamin K deficiency, so caution is advised in the presence of bleeding symptoms. To prevent the emergence of resistant organisms, it is advisable to confirm susceptibility testing and administer the minimum necessary duration. If there is a history of hypersensitivity to penicillin class drugs, the risk of severe allergic reactions is high, so it is essential to verify allergy history before administration. During administration, anaphylactic shock may occur, so patients should be monitored closely, and emergency treatment should be prepared. In the event of diarrhea after antibiotic use, consider the possibility of pseudomembranous colitis and discontinue the medication immediately and seek appropriate treatment. Long-term administration can lead to excessive growth of non-susceptible organisms, so careful monitoring is necessary when used for more than 14 days. Patients showing signs of liver dysfunction should use the drug more cautiously, as it is a drug primarily excreted by the kidneys that requires dosage adjustment in patients with renal impairment. It is recommended to avoid using this drug in patients suspected of having infectious mononucleosis. If symptoms such as hives, skin rashes, or serum sickness develop, discontinue the medication immediately and follow the doctor's instructions. Regular kidney, liver, and hematopoietic function tests should be conducted to confirm any abnormalities during long-term administration. It should be avoided in the first three months of pregnancy, and pregnant women or women who may become pregnant should administer it cautiously. During breastfeeding, this medication can be excreted in small amounts in breast milk, leading to diarrhea or hypersensitivity reactions in infants, necessitating discontinuation if any abnormal symptoms develop. It is not recommended for children under 12 years of age or weighing less than 40 kg. The elderly are at higher risk of adverse reactions due to decreased physiological function, so dosage and intervals should be adjusted, and they should be monitored carefully. Some clinical test results may be affected while taking this medication, so this should be considered during testing. In case of overdose, gastrointestinal symptoms, renal failure, seizures, and hypersensitivity shock may occur, necessitating immediate discontinuation of administration and appropriate treatment.

Serious side effects

• Hives
• severe swelling (edema)
• chest tightness
• difficulty breathing
• cold sweat
• pallor
• anaphylaxis
• Stevens-Johnson syndrome
• shock
• severe rash with high fever

Mild side effects

• Diarrhea
• pseudomembranous colitis
• indigestion
• stomatitis
• gastritis
• glossitis
• nausea
• vomiting
• loss of appetite
• abdominal pain

This medication should be stored in a sealed container to protect it from moisture, in a dry place below 25 degrees Celsius. Proper storage will help maintain the medication's effectiveness and prevent degradation.

Appearance

White or almost white oblong film-coated tablets

Package unit

100 tablets (10 tablets/PTP x 10)