Nabeton Tablets (Nabumetone)

Adult dose

This drug is for oral use. Swallow it without chewing (tablets only). Adults: Administer 1 g of nabumetone orally once daily at bedtime. If symptoms are severe or persistent, or worsen rapidly, administer an additional 500 mg∼1 g orally in the morning. Elderly patients: As with many other drugs, plasma concentrations may be higher in elderly patients. Do not exceed a maximum daily dose of 1 g; in some cases, a dose of 500 mg may provide satisfactory symptom relief.

Child dose

Children: Clinical data on the use of this formulation in children are not yet available.

This medication may cause gastric bleeding in individuals who regularly consume more than three glasses of alcohol per day, so it is essential to consult with a doctor or pharmacist. This medication may increase the risk of cardiovascular disease, and those with a history of cardiovascular disease or risk factors should exercise extra caution. If cardiovascular symptoms appear during treatment, consult a doctor immediately, and careful monitoring is required even for those without a history of cardiovascular disease. This medication may cause serious gastrointestinal adverse reactions, such as gastric bleeding, ulcers, and perforation, so elderly individuals or those with a history of gastrointestinal disorders should be administered the minimum effective dose. If symptoms of gastrointestinal bleeding or ulcer occur, stop taking the medication immediately and consult a doctor. It is advisable not to combine it with corticosteroids, anticoagulants, or other anti-inflammatory analgesics. Individuals with peptic ulcers, severe blood disorders, severe liver, kidney, or heart conditions, those with a history of aspirin-induced asthma, pregnant or nursing women, and children under 15 years should not take this medication. Those with blood disorders, liver dysfunction, kidney dysfunction, heart dysfunction, asthma, allergic rhinitis, hypertension, heart failure, autoimmune diseases, and elderly individuals should be closely monitored when taking this medication. Severe adverse reactions such as shock, anaphylaxis, severe skin rash, dyspnea, gastrointestinal bleeding, liver or kidney dysfunction, and blood disorders may occur, so if any symptoms appear, stop taking the medication and consult medical personnel immediately. This medication should not be taken with other non-steroidal anti-inflammatory drugs, and the risk of side effects may increase when combined with certain medications, so please consult with a doctor. It should particularly not be administered during pregnancy and should be avoided while nursing. Safety has not been established for children under 15, and it should not be used in this age group. Elderly patients are at higher risk for gastrointestinal bleeding and perforation, requiring careful attention during administration, and gastric conditions should be closely monitored during the first four weeks. In the case of overdose, symptoms such as headache, nausea, vomiting, gastrointestinal bleeding, and coma may occur, so prompt medical attention is necessary.

Shock, symptoms resembling anaphylaxis (difficulty breathing, hives, low blood pressure, angioedema, facial swelling), anaphylactic reactions, rash, itching, hives, dyspepsia, abdominal pain, gastric discomfort, epigastric pain, abdominal distension, loss of appetite, nausea, vomiting, hematemesis, diarrhea, constipation, pneumatosis intestinalis, gastritis, peptic ulcer, perforation, gastrointestinal bleeding, gastrointestinal disorders, bloody stools, melena, ulcerative colitis, onset or exacerbation of Crohn's disease, pancreatitis, stomatitis, xerostomia, dizziness, headache, confusion, fear, nervousness, tension, insomnia, drowsiness, paresthesia, elevated AST, elevated ALT, elevated AL-P, liver failure, hepatitis, jaundice, nephrotic syndrome, renal failure, urinary disorders, interstitial nephritis, acute tubular necrosis, papillary necrosis, elevated protein in urine, elevated BUN, elevated serum creatinine, interstitial pneumonia, fever, cough, shortness of breath, respiratory distress, bronchospasm, asthma, nosebleeds, angioedema, pseudo porphyria, hair loss, polymorphic erythema, Stevens-Johnson syndrome, toxic epidermal necrolysis, sweating, photosensitivity reactions, thrombocytopenia, neutropenia, agranulocytosis, leukopenia, leukemia, aplastic anemia, hemolytic anemia, vasculitis, hypertension, heart failure, myopathy, neck stiffness, uterine bleeding, menorrhagia, tinnitus, ear disorders, abnormal vision, visual impairment, optic neuritis, edema, fatigue, weakness, aseptic meningitis, headache, nausea, vomiting, epigastric pain, gastrointestinal bleeding, diarrhea, disorientation, agitation, coma, dizziness, tinnitus, fainting, seizures, acute renal failure, liver damage

This medication must be stored in a sealed container to prevent exposure to air and moisture. It is also advisable to keep it at room temperature between 1 degree and 30 degrees Celsius.

Appearance

1. Domestic use: white round film-coated tablets 2. Export use 1, Export use 4: yellow rectangular film-coated tablets 3. Export use 2, Export use 3: white oval film-coated tablets

Package unit

Domestic use: 30 tablets, 500 tablets/bottle Export use: 10T/PTP x 5 (50 tablets)