Centos Tablet (Terbinafine Hydrochloride)

Adult dose

As terbinafine, 125 mg once, twice a day or 250 mg once a day. The administration period varies depending on the disease as follows: 1) Dermatophytosis: Athlete's foot (interdigital, plantar/moist type): 2-6 weeks, tinea corporis: 2-4 weeks, tinea cruris: 2-4 weeks. 2) Onychomycosis: Typically administered for 6 weeks to 3 months. If the infection is in a fingernail or relatively small toe, or in younger patients, the treatment period may be shortened to less than 3 months. A general treatment duration of about 3 months is usually adequate for toenail infections, but in some patients, it may take 6 months or longer. If nails grow slowly, the treatment duration may be prolonged.

Child dose

Administer to children over 2 years of age. Tinea capitis: 4 weeks 1) <20 kg (under 5 years): 62.5 mg once a day. 2) 20-40 kg (5-12 years):

This medication should ideally not be used in patients with chronic liver disease or active liver disease. Before taking this medication, a liver function test must be performed to check for any liver function issues. Regular liver function tests should continue to be conducted 4 to 6 weeks after starting treatment to monitor liver health. If liver function test results increase, this medication should be stopped immediately, and if symptoms of liver dysfunction (nausea, loss of appetite, fatigue, vomiting, upper right abdominal pain, jaundice, dark urine, diarrhea) occur, consult a physician immediately. This medication can rarely cause liver failure, so if liver damage is suspected, use should be stopped immediately and specialized medical attention sought. Individuals with an allergy to this medication or its components should not take it. This medication is contraindicated in patients with hematological diseases (neutropenia, pancytopenia, agranulocytosis, thrombocytopenia), severe renal impairment, nursing mothers, and infants under 2 years old. Patients with genetic lactose intolerance or specific enzyme deficiencies should not take this medication. Caution should be exercised when prescribing this medication to patients with renal impairment, elderly individuals aged 65 or older, or children weighing less than 20 kg. This medication can rarely cause serious skin reactions, so discontinue use and visit a hospital if any abnormal skin symptoms arise. Patients with autoimmune diseases such as psoriasis or systemic lupus erythematosus require special caution when using this medication. This medication is metabolized in the liver, so side effects may be more severe in those with hepatic dysfunction. During treatment with this medication, symptoms such as myalgia, arthralgia, dizziness, headache, dyspepsia, nausea, rash, itching, and others may appear; if symptoms are severe, consult a physician. This medication may interact with other drugs, especially when taken concurrently with other drugs metabolized in the liver, requiring dose adjustment or caution. Women who are pregnant or may become pregnant should consult a physician before taking this medication, and nursing mothers should discontinue breastfeeding while taking this medication. Experience with this medication in young children is limited, so the decision to use it should be made cautiously. Elderly individuals may experience increased drug concentrations due to reduced liver and kidney function, so their condition should be closely observed during use. Overdose may result in headache, nausea, abdominal pain, and dizziness, requiring immediate medical treatment. This medication should be kept out of reach of children, stored in a sealed container to prevent exposure to air or moisture, and kept at room temperature between 1°C and 30°C away from direct sunlight.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, difficulty breathing or shortness of breath, asthma attack, respiratory issues accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, vision disturbances, paralysis, urination issues

Mild side effects

• Fatigue
• nausea
• loss of appetite
• vomiting
• rash
• skin itching
• fever
• abdominal bloating
• dyspepsia
• mild abdominal pain

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. It is preferable to store it at room temperature between 1°C and 30°C, avoiding extremely cold or hot places.

Appearance

White to off-white round tablet

Package unit

30 tablets/bottle, 100 tablets/bottle, 300 tablets/bottle