Medication info
Cardivine Tablet 25 mg (Carvedilol)

Cardivine Tablet 25 mg (Carvedilol)

Prescription medicationTabletOral
Ingredient · strength
Carvedilol›25mg / 1 tablet
Manufacturer / importer
Samchundang Pharm Co., Ltd.
Appearance
White round tablet
Packaging
100 tablets (10 tablets/Alu-Alu) x 10
Approval status
Active

MFDS item code 200401062 · Notified 2004.02.12 · Insurance code 651201570

Summary

Main use
Treatment of essential hypertension and chronic stable angina
Who takes it
Adults
Adult dose
Do not increase the dose or stop taking this medicine without your doctor's instructions. 1. Essential hypertension 1) Adults (1) For the first two days, administer 12.5 mg of carvedilol orally once daily, then administer 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Older adults In some older adults, 12.5 mg once daily may provide sufficient efficacy. However, if the effect is insufficient after 2 weeks of treatment, the dose may be increased. 2. Chronic stable angina 1) For the first two days, administer 12.5 mg of this medicine twice daily, then administer 25 mg twice daily. 2) The usual dose is 25 mg twice daily for 2 weeks. If a dose increase is needed (excluding older adults), the dose may be increased to 50 mg twice daily.

Ingredients

Manufacturer
Samchundang Pharm Co., Ltd.

Efficacy & effects

Treatment of essential hypertension and chronic stable angina

  • Essential hypertension
  • chronic stable angina
View approved original text

This medication is used for the treatment of essential hypertension and chronic stable angina.

How to take

Adult dose

Do not increase the dose or stop taking this medicine without your doctor's instructions. 1. Essential hypertension 1) Adults (1) For the first two days, administer 12.5 mg of carvedilol orally once daily, then administer 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Older adults In some older adults, 12.5 mg once daily may provide sufficient efficacy. However, if the effect is insufficient after 2 weeks of treatment, the dose may be increased. 2. Chronic stable angina 1) For the first two days, administer 12.5 mg of this medicine twice daily, then administer 25 mg twice daily. 2) The usual dose is 25 mg twice daily for 2 weeks. If a dose increase is needed (excluding older adults), the dose may be increased to 50 mg twice daily.

Precautions

This medication should not be used in certain patients. For example, those with an allergy to this medication or its components, severe cardiac shock or heart conduction disorders, asthma, or chronic obstructive pulmonary disease may experience worsening symptoms if taking this medication. Additionally, it is safest for patients with metabolic abnormalities due to diabetes, those with severe liver impairment, and women who are pregnant or breastfeeding not to take this medication. Before using this medication, patients with diabetes, those with a severe history of allergies, those with heart disease or elderly patients, and those with reduced kidney function should consult with a physician to be administered carefully. During use, symptoms such as dizziness, fatigue, decreased heart rate, and low blood pressure may occur, so regular monitoring of heart function and blood pressure is necessary. Esteemed caution is essential, particularly for heart failure patients, as symptoms may worsen. This medication can mask symptoms of hyperthyroidism; therefore, patients with thyroid disorders should exercise caution while taking it, and sudden discontinuation of the medication can worsen symptoms, so dosage should be tapered gradually. Furthermore, this medication may interact with various drugs; thus, when taking it with other medications, it is imperative to consult a physician or pharmacist. Special caution is needed when co-administered with antihypertensive agents, antidepressants, antiarrhythmics, and insulin. Pregnant or breastfeeding women should not take this medication, and safety for children or adolescents under 18 has not been established. Elderly patients may have reduced liver function; therefore, starting with a low dose is recommended, and close monitoring of their condition is required during treatment. In case of overdose, severe symptoms such as decreased heart rate, blood pressure drop, and cardiac shock may occur, necessitating immediate contact with a medical institution for appropriate treatment. This medication may change color due to light, so it should be stored in a shaded container, away from children. It is advisable to avoid transferring it into other containers.

Side effects

  • Dizziness
  • headache
  • fatigue
  • weakness
  • hallucination
  • confusion
  • depression
  • sleep disorder
  • nightmares
  • psychosis
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  • severe bradycardia
  • shock
  • complete atrioventricular block
  • heart failure
  • cardiac arrest
  • significant decrease in blood pressure
  • loss of consciousness
  • decreased pulse rate
  • cold extremities
  • edema
  • atrioventricular block
  • worsening heart failure
  • cardiac arrest
  • worsening kidney function
  • renal failure
  • increased airway resistance
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • constipation
  • urticaria
  • itching
  • lichen planus-like reaction
  • hyperhidrosis
  • allergic rash
  • serum aminotransferase changes
  • thrombocytopenia
  • leukopenia
  • latent diabetes onset
  • hypoglycemia
  • masking of hyperthyroidism
  • hyperglycemia
  • weight gain
  • increased blood cholesterol
  • bradycardia
  • hypotension
  • shortness of breath
  • hypertension in angina patients
  • liver function impairment
  • jaundice
  • limb pain
  • reduced tear production
  • sensory disturbance
  • visual impairment
  • eye irritation
  • dry mouth
  • urination disorder
  • sexual dysfunction
  • allergic reaction
  • toxic epidermal necrolysis
  • Stevens-Johnson syndrome
  • marked decrease in blood pressure
  • slowed heart rate
  • myocardial weakness
  • cardiac arrest
  • dyspnea
  • bronchospasm
  • vomiting
  • consciousness disturbance
  • generalized seizures

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container that prevents light exposure and air entry. The appropriate storage temperature is between 1 degree and 30 degrees Celsius at room temperature.

Appearance and packaging

Appearance

White round tablet

Package unit

100 tablets (10 tablets/Alu-Alu) x 10

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.