Cebacl Capsule 250mg (Cefaclor Hydrate)

Adult dose

As cefaclor hydrate, take 250 mg (in terms of activity) orally every 8 hours. For severe infections (such as pneumonia) and infections with low susceptibility, the dose can be doubled. For acute gonococcal urethritis, administer this drug 3g combined with 1g probenecid in a single dose.

Child dose

administer 20 mg/kg of body weight (in terms of activity) every 8 hours. In cases of severe infections, otitis media, and infections with low susceptibility, 40 mg/kg of body weight (in terms of activity) can be administered, with a maximum dose of

This medication should not be used in patients who have previously experienced severe allergic reactions or shock due to this drug. Additionally, it should be avoided by patients allergic to this drug or to cephalosporin antibiotics. Patients with a history of allergies to penicillin antibiotics or those with allergic tendencies should use it cautiously, especially those with bronchial asthma or skin rash symptoms. Patients with severely impaired kidney function, elderly patients, and those with poor nutritional status should be administered with caution, and monitoring should be performed as vitamin K deficiency symptoms may develop. Caution is also needed for patients with a history of gastrointestinal diseases, especially colitis. Rarely, this drug can cause shock or severe allergic reactions; if symptoms occur, administration should be stopped immediately and appropriate treatment should be sought. Severe skin reactions may occur, so if there are rashes, hives, or severe skin abnormalities, usage should be discontinued. Blood abnormalities may occur, making regular testing necessary, and if abnormalities are found, administration should be stopped. Since this medication can affect liver and kidney function, examinations and monitoring are required, and dose adjustments may be necessary for patients with poor kidney function. If gastrointestinal symptoms such as discomfort, diarrhea, or abdominal pain occur, immediate consultation with medical personnel is advised. Respiratory symptoms or central nervous system abnormalities may also rarely appear, necessitating caution. This drug may have interactions when used in combination with other antibiotics, so patients must inform medical personnel about any other medications they are taking. Caution is particularly needed when used with anticoagulants, diuretics, and probenecid as careful monitoring and dose adjustments are necessary. When taken with oral contraceptives, the contraceptive effect may be reduced, so additional contraceptive methods are advised. Women who are pregnant or may become pregnant should carefully consider the risks and benefits of this medication if administration is necessary, and nursing women should also use it with caution. Safety for neonates has not been established, so it is advisable not to use it in newborns under one month old. Elderly patients may exhibit adverse reactions more easily due to decreased bodily functions, so careful administration with dosage and interval adjustments is needed. This drug works by inhibiting cell wall synthesis to kill bacteria, so sensitivity tests should be performed to prevent the emergence of resistant bacteria, and it should only be used for the necessary minimum duration.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, shock, anaphylactic symptoms (generalized flushing, edema, difficulty breathing, angioedema, syncope, hypertension, vasodilation), Stevens-Johnson syndrome, toxic epidermal necrolysis, agranulocytosis, leukopenia, pancytopenia, anemia, thrombocytopenia, aplastic anemia, hemolytic anemia, hepatitis, jaundice, reversible interstitial nephritis, acute renal failure, severe colitis, interstitial pneumonia, eosinophilic lung infiltration.

Mild side effects

• Rash
• erythema
• itching
• fever
• lymphadenopathy
• arthralgia
• serum sickness-like reactions
• nausea
• vomiting
• diarrhea

This medication should be stored in a tightly closed container to prevent air and moisture ingress, and it is best kept at room temperature between 1 degree and 30 degrees Celsius. This storage helps maintain the drug's effectiveness for a longer period and ensures safe usage.

Appearance

A hard capsule with a purple upper part and a white lower part, containing a light yellow powder

Package unit

30 capsules/bottle, 100 capsules/bottle