Aprogen Clarithromycin Tablets

Adult dose

Adults: Clarithromycin is usually administered at 250mg (potency) per dose twice daily; for severe infections, administer 500mg (potency) per dose twice daily. The duration of administration is usually 7～14 days. For patients with renal failure and creatinine clearance of 30mL/min or less, reduce the dose by half. That is, administer 250mg (potency) once daily, or, for severe infections, 250mg (potency) per dose twice daily. Do not administer for more than 14 days in these patients. Mycobacterial infections: Administer 500mg (potency) of this drug per dose twice daily. In this case, it should be administered in combination with other antimycobacterial agents, such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this drug three times daily in combination with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose three times daily for 14 days (days 1～14), and administer omeprazole 40mg once daily for 28 days (days 1～28).

Child dose

Children aged 12 years and older: Same as adults. For children under 12 years, use clarithromycin dry syrup.

This medication should not be administered to patients with certain drugs or conditions. For example, it is contraindicated in patients who are allergic to any component of this medication, those with specific heart diseases, severe liver dysfunction, or significantly impaired kidney function. Additionally, it is advisable not to administer this medication to pregnant or breastfeeding women, as it can be transmitted through breast milk. Care should be taken when administering this drug to patients with impaired liver or kidney function, elderly patients, or those with heart diseases. Due to the potential for drug interactions, patients taking other medications should consult with their doctor or pharmacist. This drug can cause various side effects such as allergic reactions, gastrointestinal disorders, liver function abnormalities, kidney issues, skin rashes, central nervous system disturbances, and more, so any abnormal symptoms should be reported to medical personnel immediately. Prolonged or high-dose use of this medication may lead to hearing loss or tinnitus, so caution is necessary. To prevent antibiotic resistance, it should only be taken for the necessary duration, and if gastrointestinal problems such as diarrhea or abdominal pain occur while taking it, immediate consultation with medical personnel is advised. Moreover, this medication may cause serious side effects or altered effectiveness when taken with certain drugs, so it is crucial to consult with a specialist regarding any concurrent medications. Finally, be cautious with activities such as driving or operating machinery while taking this medication, as symptoms may vary.

shock, anaphylactic symptoms, respiratory distress, seizures, flushing, rash, itching, hives, skin redness, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, gas retention, diarrhea, oral mucosal erosion, upper abdominal pain, thirst, tooth discoloration, pancreatitis, increased amylase, taste disorder, appetite loss, constipation, stool discoloration, membranous colitis, hemorrhagic colitis, fever, cough, respiratory distress, chest X-ray abnormalities, eosinophilia, eosinophilic lung infiltrates, interstitial pneumonia, chronic bronchitis, exacerbation of acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, seizures, tremors, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, increased AST, increased ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, lethargy, headache, taste disturbance, hearing loss, paresthesia, arthralgia, myalgia, olfactory disorders, hypoglycemia, tinnitus, hearing impairment, purpuric rash, vein inflammation at the injection site, pain at the injection site, inflammation at the injection site, fever, weakness, chest pain, chills, fatigue, abnormal albumin/globulin ratio, elevated serum alkaline phosphatase, increased serum lactate dehydrogenase, increased INR, prolonged prothrombin time, discoloration of urine

This medication is sensitive to light, so it should be stored in a special container that prevents light exposure. Additionally, it should be kept at room temperature between 15 to 30 degrees Celsius to maintain efficacy.

Appearance

Yellow, rectangular film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle