Betadren Tablets (Bisoprolol Fumarate)

Adult dose

Take 5-10mg orally once daily, without chewing, along with a drink either on an empty stomach in the morning or at breakfast. In mild cases, 5mg is sufficient, while in severe cases, 10mg is administered. In special cases, up to a maximum of 20mg may be administered daily. For stable chronic heart failure, the initial dose is 1.25mg once daily, with an interval of at least 2 weeks before increasing to 2.5mg, 3.75mg, 5mg, 7.5mg, or 10mg.

Child dose

This medication is not recommended for use in children due to a lack of experience.

This medication has not been used in patients with certain diseases or conditions among heart failure patients, so caution is necessary. Particularly, patients with asthma or chronic pulmonary disease should use it along with bronchodilators and may need dosage adjustments due to possible increased airway resistance. It may increase sensitivity to allergens, so allergic reactions can occur, and adrenaline treatment may not be effective. If you have psoriasis or a history of psoriasis, you should carefully consider the risks and benefits of taking this medication. Patients with chromaffin cell tumors should use this medication after α-blockers, and symptoms of hyperthyroidism may be masked by this medication. Regular health status checks are required when starting this medication, and stopping abruptly may worsen heart conditions, so it should be tapered off gradually. Diabetic ketoacidosis, severe bradycardia, cardiogenic shock, and acute heart failure are contraindications for this medication. Pregnant women or women who could become pregnant should not take this medication as it may harm the fetus and newborn. If breastfeeding, one should avoid taking it or cease breastfeeding. Safety in children has not been established, so it is not administered to children. Elderly patients should start at a low dose and be monitored carefully, and dose adjustments may be necessary in cases of severe kidney or liver dysfunction. This medication interacts with many other drugs, so it's essential to inform the doctor of any other medications being taken. Caution is needed when used with calcium channel blockers, central nervous system drugs, etc. Caution is advised when driving or operating machinery due to individual variations in response, especially during the initial treatment phase or when changing medications. Overdose may cause symptoms such as bradycardia, hypotension, bronchospasm, worsening heart failure, or hypoglycemia, necessitating immediate medical treatment. This medication should be stored out of reach of children, and it should not be transferred to other containers from the original packaging.

Serious side effects

• Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor → severe allergic reactions
• Severe rash accompanied by high fever, blisters, peeling skin, and pain in the mouth/eyes → severe dermatological reactions
• Shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanying cough + fever → respiratory problems
• Yellowing of skin or eyes (jaundice), extreme lethargy → liver abnormalities (jaundice)
• Sudden

Mild side effects

• Cardiovascular: bradycardia, worsening heart failure, cold limbs, numbness, hypotension, atrioventricular conduction disorders, orthostatic hypotension
• Psychoneurological: dizziness, headache, sleep disorders, depression, nightmares, hallucinations
• Gastrointestinal: nausea, vomiting, diarrhea, constipation
• General: weakness, fatigue
• Respiratory: allergic rhinitis, bronchospasm
• Musculoskeletal: muscle atrophy, cramps
• Skin: hypersensitivity reactions (itching, redness, rash), worsening psoriasis, psoriatic rashes, hair loss
• Liver

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. The recommended storage temperature is between 1°C and 30°C at room temperature to maintain its effectiveness.

Appearance

A heart-shaped, yellowish film-coated tablet that is convex on both sides with a break line on one side.

Package unit

30 tablets/bottle, 100 tablets/bottle