Aromil Tablets (Glymepiride)

Adult dose

Individualized based on each patient. Swallow without chewing with over half a cup of water. This medication is taken orally once a day. It should be taken before breakfast or just before the first meal. Start dosing at 1 mg of glymepiride once a day and increase the dose by 1 mg at intervals of 1 to 2 weeks as needed. Generally, no additional effect occurs with doses over 4 mg, but some patients have shown better metabolic control at doses of up to 6

This medication should not be used in patients with insulin-dependent type 1 diabetes or those in diabetic ketoacidosis or coma. It should also not be administered in cases of allergic reactions to this medication or sulfonylureas and sulfonamides. There is no experience in using this medication in patients with severe liver or kidney dysfunction, and in such cases, switching to insulin therapy is recommended. This medication should not be used in pregnant women, women who may become pregnant, or nursing mothers. Patients with severe infections, before and after surgery, or with severe trauma may require insulin treatment. Patients experiencing gastrointestinal disturbances such as diarrhea or vomiting may have an increased risk of hypoglycemia due to improper absorption of food, so caution is advised. During the first week of taking this medication, there is a higher risk of hypoglycemia, so blood sugar levels should be monitored frequently and carefully observed. Particularly cautious measures are necessary for the elderly, patients with poor nutritional status or irregular eating patterns, and those who consume insufficient carbohydrates after intense exercise or experience changes in meal patterns. Patients frequently consuming alcohol or with impaired kidney or liver function may also have increased risk for hypoglycemia. Additionally, caution is needed for patients who overdose on this medication or have thyroid, pituitary, or adrenal dysfunction. If taking other medications, interactions that could affect blood sugar control should be discussed with a doctor. This medication has the effect of lowering blood sugar, and hypoglycemia may occur, with symptoms such as headache, severe hunger, nausea, fatigue, anxiety, confusion, dizziness, drowsiness, and loss of consciousness. Severe hypoglycemia can lead to seizures or coma, so immediate intake of sugar or medical assistance should be sought if symptoms appear. Initial doses may also produce blurred vision or gastrointestinal symptoms (nausea, vomiting, abdominal pain). Serious side effects such as liver dysfunction or decreased blood cell counts may occur rarely, and any unusual symptoms should be reported to a doctor immediately. Allergic reactions such as hives, rash, and difficulty breathing may occur, so immediate discontinuation of the medication and consultation with medical personnel should be sought if such symptoms arise. While taking this medication, it is important to maintain a regular diet, exercise, and weight management, and to periodically check blood sugar control status. In cases of hypoglycemia, rapid intake of sugar is the most effective, and it is advisable to always carry sugar. Patients and families should be adequately educated about hypoglycemia symptoms and risk factors. In stress situations or during surgery, infections, or when blood sugar control becomes difficult, temporary switching to insulin therapy may be necessary. During treatment, regular checks of blood sugar and urinalysis should be conducted to assess the medication's effect and adjust treatment as necessary. This medication may interact with other drugs, so it is essential to inform healthcare providers about new medications being taken or discontinued. In particular, there may be fluctuations in blood sugar control when taken with drugs that affect the enzymes that metabolize this medication in the liver. It is important to inform the doctor of all medications currently being taken that may raise or lower blood sugar. It is safer not to use this medication in pregnant or nursing women, and switching to insulin therapy is recommended if necessary. In children under 18, this medication's safety and efficacy have not been established, so it is best not to use it. Elderly patients may have decreased kidney function, necessitating dosage adjustments for this medication. In cases of overdose, severe hypoglycemia may occur, requiring immediate hospital care and possible treatments such as inducing vomiting, gastric lavage, or glucose injection. This medication should be stored out of reach of children, sealed in its original container.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, chest tightness, cold sweat, pallor, a severe rash accompanied by high fever, blisters, skin peeling, oral/ocular mucosal pain, jaundice (yellowing of the skin or eyes), extreme lethargy, acute severe liver dysfunction, thrombocytopenia below 10,000/μL and thrombocytopenic purpura, serious hematologic abnormalities (such as hemolytic anemia, aplastic anemia), anaphylaxis, blood

Mild side effects

• Headache
• severe hunger
• nausea
• vomiting
• fatigue
• sleep disturbances
• anxiety
• aggression
• decreased concentration
• decreased alertness or activity

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. A storage temperature of 1 to 30 degrees Celsius at room temperature is recommended. Proper storage will help maintain the medication's effectiveness over time.

Appearance

Green rectangular tablet

Package unit

30 tablets/bottle, 100 tablets/bottle