Cefaclor Dry Syrup 125mg/5mL (Cefaclor Hydrate)

Adult dose

Adults should take 250mg (based on potency) of cefaclor every 8 hours orally. For severe infections (such as pneumonia) and infections with low susceptibility, the dosage may be doubled. In acute gonococcal urethritis, this medication 3g should be administered along with probenecid 1g in a single dose.

Child dose

Pediatric patients should receive 20mg/kg (based on potency) divided every 8 hours. In cases of severe infections, otitis media, and infections with low susceptibility, a dosage of 40mg/kg (based on potency) may be administered, with a maximum dose.

This medicine works by binding to specific proteins to inhibit bacterial cell wall synthesis, thus killing the bacteria. This medicine should not be used in patients who have experienced severe allergic reactions or shock from this medicine or similar antibiotics in the past. Moreover, patients allergic to penicillin antibiotics or those with allergic tendencies, severely impaired kidney function, elderly patients, or patients with gastrointestinal diseases should be particularly cautious when using this medicine. During the use of this medication, severe allergic reactions, skin disorders, blood abnormalities, liver or kidney function problems, gastrointestinal issues, respiratory problems, or central nervous system symptoms may occur, so it is necessary to consult medical personnel immediately if any symptoms arise. To prevent the occurrence of resistant bacteria, it is advisable to check the susceptibility of the infecting bacteria and use this medication only for the minimum necessary duration. When using this medicine, it is important to thoroughly check past allergic reactions and be cautious about interactions, especially when used with other antibiotics. Particularly, when used in conjunction with certain diuretics or drugs that may affect the kidneys, careful monitoring of kidney function is necessary. There is an increased risk of bleeding when used with anticoagulants, so blood coagulation status should be monitored regularly. The contraceptive effectiveness may be reduced when used with oral contraceptives, so it is advisable to use additional contraceptive methods. Women who are pregnant or may become pregnant should use this medication only when its benefits outweigh the risks, and nursing mothers should use it cautiously as it may affect the baby. Safety for newborns less than one month old has not been established, so use should be avoided. Elderly patients should be monitored closely for side effects as they may occur more easily due to declining physical function, with adjustments made to dosage and administration intervals as required. This medicine may affect the results of certain clinical tests, so this should be communicated to medical personnel during examinations.

Serious side effects

Urticaria, swelling, respiratory distress, shock, Stevens-Johnson syndrome, toxic epidermal necrolysis, jaundice, liver abnormalities, acute renal failure, seizures, severe rash, blisters, skin peeling, severe allergic reactions, severe skin adverse reactions, respiratory problems, liver abnormalities (jaundice), severe neurological symptoms, severe swelling or urination abnormalities

Mild side effects

• General flushing
• vascular edema
• sensory disturbances
• fainting
• hypertension
• vasodilation
• rash
• erythema
• itching
• fever

This medicine is sensitive to light, so it should be stored in a container that does not allow light in. It is also recommended to store at room temperature between 1°C and 30°C to maintain its effectiveness well.

Appearance

This medicine is a pink syrup with a strawberry flavor that is dissolved when taken.

Package unit

100 grams/150 milliliters