Celltrion Clarithromycin Tablets 250 mg

Adult dose

Adults: The usual dose of clarithromycin is 250 mg (potency) twice daily. For severe infections, administer 500 mg (potency) twice daily. The usual treatment duration is 7～14 days. In patients with renal failure and a creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250 mg (potency) once daily, or, for severe infections, 250 mg (potency) twice daily. Do not administer this medicine to these patients for more than 14 days. Mycobacterial infections: Administer 500 mg (potency) twice daily. In this case, it should be given in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500 mg (potency) of this medicine three times daily for 14 days with omeprazole 40 mg once daily, followed by omeprazole 40 mg once daily for 14 consecutive days. That is, administer clarithromycin 500 mg (potency) three times daily for 14 days (days 1～14) and omeprazole 40 mg once daily for 28 days (days 1～28).

Child dose

Children aged 12 years and older: Same as adults. For children under 12 years, use clarithromycin dry syrup.

This medication should not be administered to certain patients. For example, individuals allergic to any of the ingredients in this medication or those with hypersensitivity to specific antibiotics should not take it. Furthermore, patients with arrhythmias, severe liver impairment, or significantly reduced kidney function should also not use this medication. Pregnant or breastfeeding women are advised against taking this medication. Caution is required when using this medication in patients with compromised liver or kidney function, heart disease, or the elderly. If the patient is taking other antibiotics or specific medications, it is important to be aware of potential drug interactions that could exacerbate side effects. This medication may cause various side effects, including allergic reactions, gastrointestinal issues, skin rashes, and central nervous system symptoms, so it is essential to consult a doctor immediately if unusual symptoms occur. In particular, if serious allergic reactions or signs of arrhythmia develop, treatment should be discontinued immediately. To prevent the development of resistant bacteria when using antibiotics, it is crucial to take this medication only for a necessary duration after performing sensitivity tests on the infecting bacteria. Long-term use of this medication may lead to the emergence of resistant bacteria, so it should be taken according to the physician's instructions. Pregnant or breastfeeding women should avoid taking this medication, and if unavoidable, breastfeeding should be halted. Particular caution is necessary for children and the elderly, with potential dosage adjustments required. Overdose may cause gastrointestinal disturbances or central nervous system abnormalities, and immediate treatment is necessary. This medication has numerous interactions with specific drugs, so patients must inform their doctors or pharmacists of other medications being taken. When storing, do not refrigerate and store at room temperature away from direct sunlight.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rash, itching, urticaria, skin erythema, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, discomfort, flatulence, diarrhea, oral mucosal erosion, upper abdominal pain, thirst, tooth discoloration, pancreatitis, increased amylase, taste disturbance, anorexia, constipation, discoloration of stool, pseudomembranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, derealization, convulsions, tremors, numbness, behavioral changes, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzyme levels, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, increased γ-GTP, elevated LDH, increased ALP, increased total bilirubin, elevated serum creatinine, increased BUN, interstitial nephritis, renal failure, rhabdomyolysis, stomatitis, oral mucositis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, taste disturbance, hearing loss, paresthesia, arthralgia, myalgia, olfactory disorder, hypoglycemia, tinnitus, hearing impairment, purpuric rash, acute generalised exanthematous pustulosis, muscle spasms, musculoskeletal rigidity, myopathy, elevated blood urea, phlebitis at injection site, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased International Normalized Ratio, prolonged prothrombin time, abnormal urine color

This medication should be stored in a tightly sealed container that blocks light, and it is important to maintain a storage temperature between 15°C and 30°C. Proper storage will help preserve the medication's effectiveness.

Appearance

Yellow, oval-shaped film-coated tablets

Package unit

30 tablets/bottle, 200 tablets/bottle