Nanocra Tablet 375mg [Amoxicillin, Clavulanate Potassium (2:1)]

Adult dose

For adults and children aged 12 years and above or weighing 40 kg or more, the dosage is 250 mg/125 mg of amoxicillin/clavulanate potassium per dose, taken orally three times a day every 8 hours. In cases of severe infections and respiratory infections, the dosage may be increased to 500 mg/125 mg per dose. For those with renal impairment, the dosage should be adjusted according to creatinine clearance. - Creatinine clearance 10-30 mL/min: 250-500 mg every 12 hours.

Child dose

For adults and children aged 12 years and above or weighing 40 kg or more, the dosage is 250 mg/125 mg of amoxicillin/clavulanate potassium per dose, taken orally three times a day every 8 hours. In cases of renal impairment, the dosage for adults and children must be adjusted according to creatinine clearance.

This medication is a penicillin-class antibiotic and should not be used in certain patients. In particular, patients who have had hypersensitivity reactions to this medication or beta-lactam antibiotics, individuals with infectious mononucleosis or lymphocytic leukemia, and those with a history of liver dysfunction related to this medication or penicillin should not be given this drug. Patients with poor liver function or moderate to severe renal impairment should use this medication with caution, and allergy-prone individuals or those with gastrointestinal diseases should also take care. While taking this medication, symptoms such as diarrhea, abdominal pain, or vomiting may occur, so if any abnormal symptoms appear, immediate consultation with a physician is necessary. Rarely, symptoms of hypersensitivity such as liver function abnormalities, skin rash, or respiratory difficulty may occur, so if these symptoms appear, discontinue administration and inform medical personnel. In addition, this medication may affect blood test results, so regular testing is necessary, especially monitoring liver and kidney function and blood status during prolonged use. Pregnant or nursing individuals should carefully consider the risks and benefits of using this medication, and it is advised to avoid use during early pregnancy. This medication may interact with other drugs, so it is essential to inform healthcare providers about any other medications being taken, particularly caution should be exercised when used in conjunction with anticoagulants or certain antibiotics. In case of overdose, gastrointestinal symptoms, renal impairment, or allergic reactions may occur, so the prescribed dosage must be strictly followed, and in case of any abnormal symptoms, immediate consultation with a medical facility is recommended. Lastly, this medication should be stored in a sealed container protected from air and moisture and kept in a cool, dry place below 25 degrees Celsius to maintain its efficacy.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with high fever, blisters, skin peeling, painful mucous membranes of the mouth/eyes, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanying coughing and fever, breathing problems, yellowing of the skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), sudden

Mild side effects

Diarrhea, indigestion, stomatitis, gastritis, glossitis, nausea, vomiting, loss of appetite, abdominal pain, abdominal bloating, constipation, colonic pain, hyperacidity, loose stools, dry mouth, acute pancreatitis, candidiasis, antibiotic-associated colitis, blood in stool, nausea with high dosages, increased AST, increased ALT, increased ALP, increased LDH, elevated serum bilirubin, hepatitis, cholestatic jaundice, itching, erythema multiforme, mucocutaneous syndrome (Stevens-Johnson syndrome)

This medication should be stored in a sealed container to protect it from air and moisture, and it should be kept in a cool and dry place below 25 degrees Celsius to maintain its effectiveness.

Appearance

White or almost white oval film-coated tablet

Package unit

30 tablets (6 tablets/PTP x 5)