Dr. Lamin Gold Injection

Adult dosage

In case of chronic renal failure with peripheral venous administration, adults should receive 200 mL IV drip slowly once daily. The infusion rate should be approximately 120–180 minutes per 200 mL (about 15–25 drops per minute). In high-calorie fluid therapy, adults are continuously infused with 400 mL through central vein IV. In acute renal failure, dosing can be adjusted based on age, symptoms, and weight according to high-calorie fluid therapy.

Children's dosage

In case of chronic renal failure with peripheral venous administration, the infusion rate for children should be slower than that for adults.

This medication must be used strictly according to a doctor's instructions. It should not be administered to patients with hepatic coma or those at risk of hepatic coma, as it may cause amino acid imbalance worsening symptoms. It should not be given to patients with hyperammonemia, as nitrogen overload may worsen their condition. Patients with congenital amino acid metabolism disorders should not use this medication as amino acid metabolism may be compromised, worsening symptoms. Patients with heart or circulatory problems should use this medication cautiously, as it may increase blood volume and put extra strain on the heart. Patients with liver dysfunction or gastrointestinal bleeding need to be cautious due to the potential for excessive accumulation of amino acids leading to hyperammonemia. Patients with electrolyte imbalances or acid-base balance disorders are at risk of worsening symptoms, so they should be careful as well. This medication contains sodium bisulfite, which can cause allergic reactions or asthma attacks, so especially asthmatic patients should be cautious. In case of an allergic reaction with symptoms like itching or rash, use should be discontinued immediately, and gastrointestinal symptoms such as nausea, vomiting, or loss of appetite might occur. Cardiovascular symptoms like palpitations or chest discomfort can also occur, so consultation with a doctor is advised if any abnormal signs arise. Rapid administration of this medication may cause acidosis, so it should be infused slowly. Various side effects like headache, nasal congestion, metabolic acidosis, elevated liver function tests, and abnormal kidney function may occur, so caution is necessary. This medication is used for patients who cannot take oral intake to provide non-oral nutritional support. In patients with renal failure, administration should be stopped immediately in case of altered consciousness. Women who are pregnant or may become pregnant should only use this medication when the therapeutic benefits outweigh the risks, as its safety has not been established. Caution is needed for use in children as safety has not been confirmed. Elderly patients should be administered slowly and doses adjusted due to decreased bodily function. Before administration, ensure that the solution is transparent, and if crystals have formed, heat to dissolve before use. Opened solutions should be used quickly and not reused afterward. Patients with chronic renal failure should adjust the doses considering dietary protein intake and be cautious of electrolyte balance due to sodium and acetate content. Administration speed should be slow, as rapid infusion may cause chills or vomiting and lead to greater kidney damage. In storage, do not use the medication if the packaging is damaged or if the solution has changed color, and measure accurately based on the container scale.

Serious side effects

Severe allergic reactions (anaphylaxis, asthma attacks), respiratory problems (asthma attacks), severe swelling or urine abnormalities (including full-body severe swelling), severe skin reactions (rash, blistering, skin peeling, mucosal pain), liver abnormalities (jaundice, liver dysfunction symptoms), severe neurological symptoms (confusion, seizures, severe headache, etc.)

Mild side effects

• Generalized itching
• rash
• generalized urticaria
• nausea
• vomiting
• loss of appetite
• chest discomfort
• palpitations
• headache
• nasal congestion

This medication should be stored in a sealed container to prevent air ingress and is best kept at a temperature between 1 and 30 degrees Celsius. This storage will help maintain the medication's effectiveness.

Appearance

This medication is a colorless to pale yellow transparent injection filled in a polypropylene aqueous injection container.

Package unit

250 mL