Gluris 2 mg (Glimepiride)

Adult dose

For patients who have not received treatment with a medication before, start with 1 mg of Glimepiride once daily. If needed, the dose may be increased by 1 mg at intervals of 1 to 2 weeks. Generally, there is little additional benefit at doses above 4 mg, although some patients may require an increase up to 6 mg (or 8 mg). If a dosage of 4 mg daily fails, insulin therapy can be considered.

This medication should not be used by patients with insulin-dependent diabetes or severe liver or kidney dysfunction. Additionally, it is safest not to administer it to women who are pregnant or breastfeeding. During the first week of treatment, there is a heightened risk of hypoglycemia, so blood sugar should be monitored very closely. Elderly patients, those with poor nutritional status or irregular eating patterns, and individuals who consume alcohol frequently may have a higher risk of hypoglycemia. Symptoms of hypoglycemia may include headache, severe hunger, nausea, fatigue, confusion, drowsiness, and loss of consciousness, so immediate intake of glucose is necessary when these symptoms occur. During the course of this medication, it is important to maintain regular meals and exercise and to regularly monitor blood sugar levels. Moreover, when taken with other medications, it may affect blood sugar control; therefore, patients should inform their doctor or pharmacist about any other medications they are taking. Interactions may occur, especially with beta-blockers, antibiotics, and anticoagulants. In case of overdose, serious hypoglycemia can occur, and immediate medical attention should be sought for appropriate treatment. The safety and efficacy of this medication in children have not been established, and for the elderly, dosage adjustments may be necessary due to potential reduced kidney function. Lastly, store this medication out of reach of children and in its original container for safety.

Serious side effects

Hives, severe swelling (edema), notify a doctor immediately if hives appear, difficulty breathing, hypotension, shock, anaphylaxis, angioedema, skin and mucous membrane syndrome (Stevens-Johnson syndrome), liver dysfunction (cholestasis, jaundice, hepatitis), severe hypoglycemia (seizures, coma, loss of consciousness), thrombocytopenia, leukopenia, hemolytic anemia, erythrocytopenia, granulocytopenia, agranulocytosis, pancytopenia, and blood.

Mild side effects

Symptoms of hypoglycemia (headache, severe hunger, nausea, vomiting, fatigue, sleep disturbances, anxiety, aggression, decreased concentration, reduced alertness or activity, depression, confusion, speech disturbances, visual disturbances, tremors, incomplete paralysis, sensory disturbances, dizziness, weakness, loss of self-control, transient mental confusion, drowsiness, loss of consciousness, shallow breathing, bradycardia, etc.), blurred vision, nausea, vomiting, upper abdominal fullness, pressure, abdominal pain, diarrhea, liver function.

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. The recommended storage temperature is between 1°C and 30°C (room temperature). Storing it this way will help maintain the medication's effectiveness.

Appearance

Green, rectangular tablet

Package unit

30 tablets/bottle, 300 tablets/bottle