Diliid Injection 2 mg (Hydromorphone Hydrochloride)

Adult administration

(Injection) * 1, 2, 4 mg/mL The initial dose is 1 ∼ 2 mg administered subcutaneously or intramuscularly every 4 ∼ 6 hours, depending on the severity of pain. Adjust the dose appropriately according to the severity of pain, the patient's underlying conditions, age, and body size. Patients with terminal cancer may develop strong tolerance to opioid analgesics and may require higher doses for adequate pain relief. Intravenous administration may be used if necessary, but the injection must be given slowly over at least 2 ∼ 3 minutes. Rapid intravenous administration of opioid analgesics may increase the risk of hypotension and respiratory depression. If tolerance develops or the pain worsens, gradual dose escalation may be necessary. The first sign of developing tolerance is generally a shorter duration of the medication's effect. * Before administration, visually inspect the injection for discoloration and particulate matter. The solution in the ampoule may become pale yellow, but this does not reduce the effect of this medicine.

This medication should be handled with care when opening the ampoule container, as glass fragments may enter. Special care should be taken when using this medication for children or the elderly. This drug has a central nervous system suppressive action, so caution is necessary when used with alcohol or certain sedatives, as it may lead to severe drowsiness, respiratory cessation, coma, or even death. This medication should not be used in patients with specific conditions. For example, it may be dangerous for patients with drug allergies, increased intracranial pressure, severe respiratory difficulty, heart or lung problems, or women who are pregnant. Elderly patients or those with impaired kidney function or hypothyroidism should use this drug with increased caution, as the likelihood of adverse reactions may increase, requiring careful monitoring. Long-term use of this medication may lead to dependence; therefore, sudden reduction or cessation of usage may result in withdrawal symptoms. There are respiratory suppressive side effects, so if symptoms of difficulty in breathing or irregular breathing occur, medical personnel should be notified immediately. This medication suppresses the cough reflex, making it essential to use caution in patients with lung disease, as drowsiness or dizziness may occur during dangerous activities such as driving or operating machinery. This medication can interact with other drugs; therefore, careful dosage adjustment and monitoring are necessary, especially when used with other central nervous system suppressants or specific antidepressants and narcotic analgesics. Pregnant or breastfeeding women should not use this medication; breastfeeding should be discontinued as the drug can be transmitted through breast milk. In case of overdose, severe respiratory suppression, loss of consciousness, and hypotension may occur; immediate emergency treatment is necessary, and appropriate treatment should be followed as directed by medical personnel. When administered as an injection, it should be injected slowly, as rapid injection may lead to severe side effects such as hypotension or respiratory suppression.

Yawning, sneezing, tearing, sweating, nausea, vomiting, diarrhea, abdominal pain, pupil dilation, headache, insomnia, anxiety, hallucinations, seizures, tremors, pain in muscles and joints throughout the body, breathlessness, palpitations, dyspnea, slow breathing, irregular breathing, apnea, head injury, increased intracranial pressure, hypotension, shock, sedation, drowsiness, confusion, impaired mental and physical performance, craving, fear, discomfort, psychological dependence, emotional changes, mental unrest, dizziness, weakness, excitement, motor disturbances, rigidity, abnormal sensations, muscle twitching, visual disturbances, nystagmus, miosis, double vision, transient hallucinations, burning sensation, euphoria, sweating, central sleep apnea syndrome, hyperalgesia, thirst, constipation, biliary colic, intestinal obstruction, loss of appetite, gastric cramps, taste changes, coldness, tachycardia, bradycardia, flushing, syncope, hypotension, hypertension, circulatory disorders, peripheral circulatory collapse, cardiac arrest, orthostatic hypotension, ureteral spasm, bladder sphincter spasm, urinary retention, bronchospasm, laryngeal spasm, itching, urticaria, other skin rashes, seizures, myoclonic seizures, unconsciousness, coma, skeletal muscle relaxation, cool skin, miosis, bradycardia

This medication may be sensitive to light; thus, it should be kept sealed in a container that does not allow light to enter. The storage temperature should be maintained between 1 to 30 degrees Celsius (room temperature). Doing so will help maintain the drug's efficacy and safety for a longer period.

Appearance

Brown ampoule containing a colorless transparent solution

Package unit

1mL X 10 ampoules