CAPD 18 Balance Peritoneal Dialysis Solution (Imported Name: Balance 4.25% glucose, 1.25 mmol Calcium, Peritoneal Dialysis Solution)

Adult administration

Typically, in adults, 1.5 to 2.5L is infused into the abdomen and drained after retaining for 4 to 8 hours, 3 to 5 times a day.

This drug is a dialysis solution used for peritoneal dialysis, aiding in the removal of waste products from the body in patients with severely impaired kidney function. Sudden cessation of peritoneal dialysis may pose a life-threatening risk; therefore, it should not be stopped prematurely unless alternative renal replacement therapies are in place. It should not be used in patients with defects of the diaphragm or severe abdominal burns, or those with severe abdominal adhesions as this may lead to respiratory difficulties or reduced dialysis efficiency. Patients with a tendency to bleed, lactic acidosis, severe hypokalemia, or hypocalcemia should not use this medication. Recent abdominal surgeries, severe inflammation, abdominal fistulae, tumors, bowel obstructions, severe pulmonary diseases, sepsis, or significant weight loss necessitate careful assessment prior to use. This medication must be used precisely as directed by a physician, and aseptic techniques must be observed to avoid risks of peritonitis or infection. During dialysis, it is necessary to periodically check weight, serum electrolyte levels, blood glucose, and protein levels for any abnormalities. Patients using this medication may experience side effects such as abdominal pain, bleeding, peritonitis, electrolyte imbalance, gastrointestinal symptoms, respiratory distress, and edema. In particular, patients taking digitalis medications or with glucose metabolism disorders should frequently monitor their potassium levels and blood glucose levels. Women who are pregnant or breastfeeding should only use this medication when the benefits outweigh the risks, as safety has not been established. Dosing for pediatric patients should be adjusted according to age and weight, while elderly patients should consider the risk of hernia before initiating peritoneal dialysis. The dialysis solution should be used directly from the provided container, and should not be used if the packaging is damaged or if the solution is cloudy. The peritoneal dialysis solution should be warmed to body temperature before use and stored at room temperature, avoiding direct sunlight and freezing. Excessive dosing or rapid exchanges may lead to dehydration, electrolyte imbalances, or hyperglycemia, and if abnormalities occur, immediate medical attention should be sought.

Serious side effects

• Peritonitis (abdominal pain, possibility of cloudy drainage and fever).
• Sepsis (related to peritoneal dialysis process).
• Bowel obstruction.
• Respiratory distress due to diaphragm defects.
• Severe edema and urination abnormalities.
• Severe allergic reactions (hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor).
• Severe dermatological reactions (severe rash, blistering, skin peeling, oral/ocular mucosal pain accompanied by high fever).
• Respiratory issues (shortness of breath or difficulty breathing, wheezing).

Mild side effects

• Abdominal pain, bleeding, peritonitis (abdominal pain, cloudy drainage sometimes accompanied by fever), inflammation around the abdominal catheter (redness, discharge), catheter breakage or subcutaneous inflammation due to drainage difficulties.
• Nausea, abdominal pain, diarrhea, constipation, hemorrhoids, vomiting, loss of appetite, abdominal bloating, bowel obstruction.
• Hypokalemia, hyponatremia, hypocalcemia, hypophosphatemia, hyperlactatemia, hypomagnesemia.
• Hypercholesterolemia, hypertriglyceridemia, metabolic acidosis.

This medication must not be stored at temperatures below 4 degrees Celsius. Therefore, care should be taken to avoid excessive cold storage.

Appearance

Colorless and transparent solution divided into two solutions: Solution A (left) in a λ-shaped bag and Solution B (right)

Package unit

100 bags/box [2,000 mL/bag x 1 piece], 400 bags/box [2,000 mL/bag x 4 pieces]