Frito Plus Tablet 40/12.5 mg

Adult dose

Patients whose blood pressure is not adequately controlled by Telmisartan alone may take this medication once daily with or without food. Telmisartan/Hydrochlorothiazide combination 40/12.5 mg may be administered to patients not controlled by 40 mg of Telmisartan. Combination 80/12.5 mg may be administered to patients not controlled by 80 mg of Telmisartan, and combination 80/25 mg may be administered to patients not adequately controlled with 80 mg of Telmisartan and hydrochlorothiazide 12.5 mg alone or in combination. Before starting this medication, sodium or blood volume depletion should be corrected. For patients with renal impairment, dosage adjustment is not required for mild to moderate renal impairment. This medication should not be administered to patients with severe renal impairment (creatinine clearance <30 mL/min). Regular monitoring of kidney function is recommended. For patients with liver impairment, this medication should be administered with caution. Dosage should not exceed 40/12.5 mg per day. This medication should not be administered to patients with severe liver impairment (see precautions 2). Thiazide diuretics should be administered with caution in patients with liver dysfunction. For elderly patients, dosage adjustment is not required. For pediatric patients, the safety and efficacy of this medication have not been established in those under 18 years of age.

Child dose

The safety and efficacy of this medication have not been established in patients under 18 years of age, so it is not to be administered.

This medication can cause serious side effects and death to the fetus if taken during pregnancy, especially in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. Additionally, it should not be administered to patients with allergies to its components or specific liver or kidney disorders, and should be avoided by pregnant and breastfeeding women. Elderly patients or those with high potassium levels or impaired liver function should exercise extra caution when using this medication. The hydrochlorothiazide component may cause electrolyte imbalance, so regular monitoring of blood potassium, sodium, magnesium, and other levels is necessary. While taking this medication, symptoms such as dizziness, hypotension, muscle cramps, nausea, and vomiting may occur, and immediate consultation with healthcare professionals is required in case of unusual symptoms. Furthermore, this medication may interact with other antihypertensives, diuretics, lithium, potassium supplements, etc., so it is essential to inform the physician or pharmacist if other medications are being used. Caution is advised when driving or operating machinery as drowsiness or dizziness may occur. This medication may increase sensitivity to sunlight, so it is crucial to manage UV protection while taking it, and any skin abnormalities should be reported to healthcare professionals immediately. In cases of overdose, symptoms such as hypotension, electrolyte imbalance, and dehydration may occur, and immediate hospital treatment must be sought. Finally, this medication is not recommended for children due to the lack of established safety and efficacy.

Serious side effects

• Hives
• angioedema (including fatal outcomes)
• difficulty breathing
• angioedema (including fatal outcomes)
• angioedema
• severe swelling (edema)
• angioedema
• angioedema (including fatal outcomes)
• angioedema (including fatal outcomes)
• angioedema (including fatal outcomes)

Mild side effects

• Dizziness
• diarrhea
• cough
• pharyngitis
• sinusitis
• hypokalemia
• hyperuricemia
• hyponatremia
• anxiety
• depression

This medication may be sensitive to air or moisture, so it should be stored in a sealed container. The storage temperature should be between 1 to 30 degrees Celsius at room temperature to maintain the drug's effectiveness.

Appearance

This is a white-red, biconvex, oblong tablet and may have red specks in the white layer.

Package unit

30 tablets/box [(10 tablets/PTP x 3)]