Apex Tablet (Aceclofenac)

Adult dose

For aceclofenac, take 100 mg once every 12 hours, twice a day. Do not chew or crush this medication; take it as is. Adjust the dosage appropriately based on symptoms. To minimize cardiovascular adverse reactions, administer at the lowest effective dose for the shortest duration.

This medication should be consulted with a doctor or pharmacist before taking for individuals who regularly consume more than three glasses of alcohol daily. There is a risk of gastrointestinal bleeding if this medication is taken by heavy drinkers. This medication may increase the risk of cardiovascular and cerebrovascular issues. Patients with risk factors for heart disease or cerebrovascular disease should use this medication cautiously, taking the minimum effective dose for the shortest duration possible. Also, cardiovascular symptoms should be monitored periodically during treatment. There are risks associated with the gastrointestinal tract, including serious adverse reactions such as bleeding, ulcers, or perforation in the stomach or intestines. Particularly, elderly patients or those with a history of gastrointestinal disease should be cautious, and if gastrointestinal symptoms occur, they should notify medical personnel immediately. Patients with active peptic ulcers or bleeding, or those with allergies to this medication or similar drugs, asthma or heart failure patients, patients with severe kidney or liver diseases, pregnant women in late pregnancy, and nursing mothers should not take this medication. Patients with kidney impairment, heart failure, hypertension, or liver impairment should exercise special caution when taking this medication, and regular tests as per medical advice are required. This medication can cause central nervous system side effects such as dizziness or drowsiness, so it is advisable to avoid driving or operating dangerous machinery while taking it. In late pregnancy, it may harm the fetus, so women who are pregnant or planning to become pregnant should consult a doctor before taking it. Moreover, nursing mothers should either stop breastfeeding or avoid taking this medication. This medication may interact with other drugs, so consult your doctor especially if you are taking anticoagulants, diuretics, antihypertensives, or diabetes medications. Long-term use requires regular monitoring of liver and kidney functions, as well as blood tests to check for abnormalities. In case of overdose, symptoms such as gastric irritation, hypotension, respiratory depression, and convulsions may occur, so it is essential to visit a medical facility immediately. The safety and efficacy of this medication have not been established in children, and the risk of adverse effects such as gastrointestinal bleeding is higher in the elderly, so caution is needed. Lastly, store this medication out of reach of children and avoid transferring it to another container as it may not be conducive to maintaining quality.

Serious side effects

• Hives
• severe swelling (edema)
• difficulty breathing
• severe allergic reactions
• severe rash with high fever
• blisters
• skin peeling
• pain in oral/ocular mucous membranes
• severe skin adverse reactions
• jaundice

Mild side effects

• Dizziness
• abnormal liver enzyme levels
• itching
• rash
• skin adverse reactions
• anemia
• blood-related abnormalities
• hyperkalemia
• depression
• strange dreams

This medication should be stored in a tightly closed container to prevent air and moisture from entering. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle