Agafen Tablet (Aceclofenac)

Adult dose

As aceclofenac, take 100 mg twice a day, every 12 hours. This medication should be taken whole without chewing or crushing. Adjust dosage as appropriate based on symptoms. To minimize cardiovascular side effects, it should be administered at the lowest effective dose for the shortest duration.

This medication may increase the risk of gastrointestinal bleeding for those who regularly consume more than three glasses of alcohol a day, so it is essential to consult a doctor or pharmacist. It may increase the risk of cardiovascular diseases; hence, patients with risk factors such as heart conditions, hypertension, or diabetes should start treatment carefully and take the lowest dose for the shortest duration possible. It can cause severe gastrointestinal issues such as gastrointestinal bleeding, ulcers, or perforation, so elderly patients or those with a history of gastrointestinal diseases should exercise special caution. Patients with active peptic ulcers or bleeding, or those who have an allergic reaction to this medication or other drugs in the same class should not take this medication. Patients with heart failure, severe kidney or liver impairment, pregnant women in late pregnancy, nursing mothers, and patients with inflammatory bowel disease are also prohibited from taking this medication. Patients with a history of renal impairment, heart failure, hypertension, or asthma should use it cautiously and must be closely monitored during treatment. This medication may cause various side effects, such as dizziness, gastrointestinal disturbances, increased liver enzyme levels, and skin rashes. If abnormal symptoms occur, immediate consultation with a healthcare professional is advised. If symptoms of cardiovascular issues, signs of gastrointestinal bleeding, or severe skin reactions occur, discontinue the medication immediately and seek treatment. Use during pregnancy, particularly in late stages, may harm the fetus, so women who are pregnant or planning to become pregnant should avoid taking this medication. There are many potential drug interactions, so if taken with digoxin, anticoagulants, diabetes medication, diuretics, etc., consultation with a physician is essential. During treatment, regular monitoring of blood pressure, kidney, and liver function is necessary, along with paying attention to symptoms of bleeding or allergic reactions. Safety in children and adolescents has not been established, and elderly patients face a higher risk of gastrointestinal bleeding, necessitating special caution. In the event of an overdose, gastrointestinal irritation, hypotension, respiratory depression, and seizures may occur, requiring immediate medical attention. Store this medication out of reach of children and do not transfer to another container for safety.

Serious side effects

Urticaria, severe swelling (edema), severe allergic reactions, high fever with severe rashes, blisters, skin peeling, pain in the oral/eye mucous membranes, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, respiratory issues, yellowing of the skin or eyes (jaundice), extreme fatigue, liver abnormalities (jaundice), sudden and severe headaches, thunderclap headaches, seizures, loss of consciousness.

Mild side effects

• Dizziness
• abnormal liver enzyme levels
• itching
• rash
• facial flushing
• hypertension
• heart failure
• respiratory distress
• bronchospasm
• wheezing

This medication may be sensitive to air and moisture; therefore, it should be stored in a tightly closed container. It is advisable to maintain the storage temperature between 1 and 30 degrees Celsius at room temperature to preserve the effect and safety of the medication for an extended period.

Appearance

White, round, film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle