Verast Tablet (Beraprost Sodium)

Adult dose

Improvement of ulcers, pain, and coldness associated with chronic arterial occlusive disease (such as Buerger's disease, arteriosclerosis obliterans, and diabetic peripheral angiopathy): Adults usually take 0.12mg (6 tablets) of beraprost sodium per day orally after meals, divided into 3 doses (2 tablets per dose). Primary pulmonary hypertension: 1) Adults usually begin by taking 0.06mg (3 tablets) of beraprost sodium per day orally after meals, divided into 3 doses (1 tablet per dose), and gradually increase the dose while carefully monitoring symptoms (adverse reactions). If the dose is increased, the frequency of administration should be 3-4 times daily, with a maximum dose of 0.18mg (9 tablets) per day. 2) Since patients vary in their tolerance to the medicine, begin administration of this product at a low dose. If the dose is increased, closely monitor the patient's condition. 3) Since this product is an oral formulation, it may be ineffective in patients with severe symptoms. If hemodynamic parameters and/or clinical symptoms do not improve sufficiently, provide appropriate treatment, such as switching to an injectable formulation or another treatment.

This medication should not be used in patients with bleeding. Individuals with bleeding disorders such as hemophilia or gastrointestinal bleeding may be at risk when taking this medication. Women who are pregnant or may become pregnant should not take this medication as it may affect the fetus. Since it contains lactose, patients with lactose intolerance or certain genetic metabolic disorders should not take this medication. Patients taking anticoagulants, antiplatelet agents, or thrombolytics should use this medication cautiously and consult a doctor, as the risk of bleeding may increase. Patients who are menstruating or have a tendency to bleed should also be cautious. Patients with severely reduced kidney function should use this medication carefully as its concentration in the body may increase. This medication can rarely cause serious bleeding, shock, liver dysfunction, pneumonia, and heart-related issues, so if abnormal symptoms occur, immediately discontinue use and consult a healthcare professional. Side effects such as headaches, diarrhea, nausea, rashes, and changes in blood pressure may occur, and symptoms should be monitored closely. There may be a risk of consciousness disturbance, so caution is needed when driving or operating machinery. There may be interactions when used with other anticoagulants or antihypertensives, so it is essential to inform a doctor or pharmacist. Pregnant or breastfeeding women are advised to avoid this medication, and in unavoidable cases, breastfeeding should be discontinued. Safety in children has not been established, so administration to children should be done with caution. Elderly individuals may require dosage adjustments as physical functions may decline. Store in a safe place out of the reach of children, and it is advisable not to transfer to other containers.

• Cerebral hemorrhage
• gastrointestinal bleeding
• retinal hemorrhage
• pulmonary hemorrhage
• shock
• syncope
• loss of consciousness
• interstitial pneumonia
• liver dysfunction
• jaundice

This medication should be stored in a tightly closed container to prevent exposure to air or humidity. It is important to keep the storage temperature between 1 degree and 30 degrees Celsius.

Appearance

White to pale yellow round film-coated tablet with no odor.

Package unit

30 tablets/bottle, 100 tablets/bottle