Clara Tablets 500 mg (Clarithromycin)

Adult dose

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily; for severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7～14 days. In patients with renal impairment and creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer to these patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) of this drug twice daily. In this case, it must be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this drug three times daily with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) three times daily for 14 days (days 1–14), and omeprazole 40mg once daily for 28 days (days 1–28).

Child dose

Children aged 12 years and older: Same as adults. For children under 12 years, use clarithromycin dry syrup.

This medication should not be used in patients with known allergies to its specific components. Patients who have previously shown hypersensitivity to clarithromycin or similar classes of antibiotics should also not receive this medication. Patients with a history of QT interval prolongation or cardiac arrhythmias should use this medication cautiously due to the risk of worsening cardiac conditions. Those with severe liver or kidney impairment require careful evaluation before administration due to potential issues with drug metabolism and excretion. It is safer for pregnant or breastfeeding women to avoid this medication. There may be an increased risk of side effects when used in combination with certain other medications, so consultation with healthcare providers is essential. During treatment, symptoms such as allergic reactions, gastrointestinal disturbances, hearing impairments, and skin rashes may occur, so healthcare providers should be notified immediately of any such symptoms. Long-term or excessive doses may lead to serious side effects such as liver dysfunction, kidney impairment, and muscle damage, thus requiring regular monitoring. To prevent the emergence of antibiotic-resistant strains, it is important to adhere to the dosage and duration recommended by the physician. Caution should be exercised when driving or operating machinery due to the potential for dizziness or confusion. Particularly in elderly patients or those with weakened immune systems, side effects may be more pronounced, requiring heightened vigilance.

Shock, anaphylactic symptoms, dyspnea, seizures, flushing, rash, itching, urticaria, skin flushing, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, gas retention, diarrhea, oral mucosal erosion, upper abdominal pain, convulsion pattern, dry mouth, transient tooth discoloration, pancreatitis, increased amylase, taste disturbance, anorexia, constipation, stool discoloration, membranous colitis, hemorrhagic colitis, bloody stool, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltrates, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, increased γ-GTP, elevated LDH, increased ALP, total bilirubin increase, anorexia, dark urine, pruritus, abdominal tenderness, elevated serum creatinine, increased BUN, interstitial nephritis, kidney failure, rhabdomyolysis, myalgia, weakness, elevated CPK, increased serum myoglobin, increased urinary myoglobin, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, taste disturbance, hearing loss, paresthesia, arthralgia, myalgia, olfactory disturbance, hypoglycemia, tinnitus, hearing loss, vomiting, purpuric rash, acute generalized exanthematous pustulosis (AGEP), muscle cramps, musculoskeletal stiffness, myopathy, elevated blood urea nitrogen, nephritis, phlebitis at the injection site, pain at the injection site, inflammation at the injection site, fever, asthenia, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated alkaline phosphatase, increased lactate dehydrogenase, increased International Normalized Ratio, prolonged prothrombin time, abnormal urine color, cardiac arrest, atrial fibrillation, ECG QT prolongation, premature contractions, palpitations, vasodilation, bleeding, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, hyperhidrosis, papular rash, acne, Henoch-Schonlein purpura, musculoskeletal and connective tissue disorders

This medication should be stored in a tightly sealed container that blocks light, at room temperature between 15 and 30 degrees Celsius. This storage method helps maintain the drug's efficacy and safety.

Appearance

Yellow, oblong film-coated tablet

Package unit

30 tablets, 100 tablets