Gliwon Tablet 2mg (Glimepiride)

Adult dose

For patients who have not previously received medication, treatment should begin with 1 mg of Glimepiride once daily. If necessary, the dose may be increased by 1 mg at intervals of 1 to 2 weeks. Generally, there is little additional benefit above a dose of 4 mg, but some patients have shown better metabolic control with doses of 6 mg (or 8 mg). Administering 4 mg once daily can lead to optimal outcomes.

This medication should not be used in patients with insulin-dependent diabetes mellitus or those with diabetic ketoacidosis or diabetic coma. Patients with allergies to this medication or its components, or to any sulfonylureas, should also avoid it. It has not been used in patients with severely impaired liver or kidney function, and in such cases, transitioning to insulin therapy is recommended. Women who are pregnant, may become pregnant, or are breastfeeding should not take this medication. It is also advisable for patients with severe infections, pre-and post-surgery, or significant trauma to receive insulin therapy. In cases of gastrointestinal disturbances such as diarrhea or vomiting, caution is needed as the absorption of food may be impaired, increasing the risk of hypoglycemia. During the first week of medication use, the risk of hypoglycemia is heightened, and blood sugar levels should be monitored frequently, especially in the elderly or those with poor nutritional status, irregular eating habits, or an imbalance between exercise and food intake. There is also an increased risk of hypoglycemia in individuals who regularly consume alcohol or have compromised kidney or liver function. Those who have overdosed on this medication or have endocrine disorders may also be sensitive to hypoglycemia. Furthermore, the elderly or those taking other medications should also be cautious about fluctuations in blood sugar and must inform their physician or pharmacist about all medications they are currently taking and their health status. Symptoms of hypoglycemia may occur when taking this medication, which can present as headaches, severe hunger, nausea, fatigue, anxiety, confusion, drowsiness, or loss of consciousness. Hypoglycemia typically resolves quickly with the intake of sugar, so it is crucial to always carry sugar. Blurred vision, gastrointestinal symptoms, liver function abnormalities, blood disorders, and allergic reactions may occur rarely, and if any unusual symptoms appear, immediate consultation with a doctor is required. In the case of severe allergic reactions, the medication should be stopped immediately, and treatment should be sought. This medication should be taken regularly in conjunction with dietary modifications and exercise to control blood sugar and, if blood sugar is poorly controlled, adjustments in treatment methods should be discussed with a doctor. Educating patients and their families about the symptoms and risks of hypoglycemia is crucial. In situations of stress such as trauma, surgery, or infections, blood sugar control may become difficult, so a temporary transition to insulin therapy may be necessary. When taking this medication with other drugs, it may affect blood sugar control, so all medications being taken should be disclosed to the doctor or pharmacist. Particularly, there may be interactions with specific antibiotics, anticoagulants, steroids, beta-blockers, etc. Women who are pregnant or breastfeeding should not take this medication due to potential risks to the fetus or newborn. If necessary, transitioning to insulin therapy is advised. The safety and efficacy in pediatric patients under 18 years of age have not been established. The elderly may have impaired kidney function, so caution in dosage adjustments is essential. In case of overdose, severe hypoglycemia may occur, requiring immediate emergency treatment, and glucose injections or other treatments should be administered as directed by a physician. This medication should be stored out of reach of children, and it is safest to keep it in its original container without transferring it to another.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, severe allergic reactions (anaphylaxis, angioedema, Stevens-Johnson syndrome), liver function abnormalities (jaundice, hepatitis, liver failure), thrombocytopenia, leukopenia, hemolytic anemia, erythrocytopenia, agranulocytosis, pancytopenia, severe edema, coma due to severe hypoglycemia, seizures, serious neurological symptoms (confusion, visual disturbances, paralysis), hypotension, shock.

Mild side effects

• Headache
• severe hunger
• nausea
• vomiting
• fatigue
• sleep disturbances
• anxiety
• aggressiveness
• decreased concentration
• reduced agility or activity

This medication should be stored in a tightly sealed container to protect it from exposure to air and moisture. It is important to maintain a storage temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness and safety over time.

Appearance

Green rectangular tablet

Package unit

30 tablets/bottle, 100 tablets/bottle